Evidence-Based Endocrinology (Contemporary Endocrinology)

Internationally recognized experts, pioneers, and opinion makers in evidence-based medicine (EBM) provocatively recast endocrine policy and practice in the light of EBM philosophy and principles. The authors explain the past, present, and future of EBM; consider its practical implications for endocrinology; demonstrate what the "evidence base" is in EBM; and present illustrative case studies by practicing evidence-based clinicians. Highlights include essays on why cost-effective analyses are problematic, the contrast between clinical investigations and large randomized trials, the role of Cochrane reviews and meta-analyses, and the curriculum requirements for training evidence-based endocrinologists.

The New Endocrinologist: Evidence-Based Medicine Meets Endocrine Practice
Victor M. Montori
Part I. Past, Present, and Future
A Short History of Evidence-Based Medicine: Issues for the Clinician
Jeanne Daly
The Philosophy of Evidence-Based Medicine
Gordon H. Guyatt and Jason W. Busse
Preparing Future Generations of Evidence-Based Endocrinologists
Michael L. Green
Part II. Practicing Evidence-Based Endocrinology
Finding Current Best Evidence in Endocrinology
R. Brian Haynes and Cynthia J. Walker-Dilks
Integrating Evidence Into Clinical Diagnosis
W. Scott Richardson
Supporting Evidence-Based Endocrine Practice
Steven A. Smith and Geoffrey S. Gates
Supporting Patients' Participation in Decision Making
Annette M. O'Connor, Dawn Stacey, and France Légaré
Incorporating Evidence Into Health Policy Decisions
Eduardo Ortiz and Janelle Guirguis-Blake
Part III. Research Evidence for Evidence-Based Endocrine Practice
The Value of Observational Studies in Endocrinology
L. Joseph Melton III
Clinical Research Center-Based Investigations and Evidence-Based Medicine
William L. Isley
The Value of Systematic Reviews in Endocrinology: The Impact of the Cochrane Metabolic and Endocrine Disorders Review Group
Bernd Richter
Health-Related Quality-of-Life Assessment in Endocrinology
Elie A. Akl and Holger J. Schünemann
Decision Analysis in Endocrinology
Evelyn Mentari and David Aron
Clouded Thinking: The Misguided Use of Cost-Effectiveness Analysis and the Implications for Endocrine Interventions
Amiram Gafni
Translation Research in Diabetes: Asking Broader Questions
Russell E. Glasgow, Elizabeth Bayliss, and Paul A. Estabrooks
Part IV. Case Studies in Evidence-Based Practice
The Patient WithType 1 Diabetes and Hypoglycemia
Yogish C. Kudva, Teck-Kim Khoo, and Peter J. Tebben
The Patient With Medically Complicated Obesity
Kurt A. Kennel
The Patient at Risk for Diabetes: Considering Prevention
Sarah E. Capes
An Evidence-Based Approach to Type 2 Diabetes
Robert K. Semple and Sean F. Dinneen
Patients With Diabetes Using Alternative Medicine
Dugald Seely, Edward Mills, and Beth Rachlis
Evidence-Based Case Studies in Osteoporosis
Clifford J. Rosen and Sue A. Brown
The Neuroendocrinology of Medically Unexplained Syndromes: The Example of Chronic Fatigue Syndrome
Jason W. Busse
Index