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Modern Mechanobiology
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Convergence of Biomechanics, Development, and Genomics
Besorgungstitel - wird vorgemerkt | Lieferzeit: Besorgungstitel - Lieferbar innerhalb von 10 Werktagen I
Artikel-Nr:
9789814800587
Veröffentl:
2021
Erscheinungsdatum:
25.02.2021
Seiten:
262
Autor:
Juhyun Lee
Gewicht:
517 g
Format:
229x152x16 mm
Sprache:
Englisch
Beschreibung:
Juhyun Lee is assistant professor of bioengineering at the University of Texas at Arlington. He completed his BS, MS, and PhD in biomedical engineering from the University of Utah, the University of Southern California, and the University of California, Los Angeles, respectively. He also studied cardiac chamber development in response to biomechanical forces. Dr. Lee has published more than 49 peer-reviewed articles. Over the past few years, he has focused on novel optical systems design, and cardiac development and regeneration.
Modern mechanobiology converges both engineering and medicine to address personalized medicine. This book is built on the previously well-received edition, Hemodynamics and Mechanobiology of Endothelium. The central theme focuses on "omic" approaches to mechanosignal transduction underlying tissue development, injury, and repair.
1. Shear Stress, Mechanosensors, and Atherosclerosis 2. Role of Krüppel-Like Factors in Endothelial Cell Function and Shear Stress-Mediated Vasoprotection 3. Aortic Valve Endothelium Mechanobiology 4. Mechanotransduction of Cardiovascular Development and Regeneration 5. Mechanotransduction in Heart Formation: An Avian Model for Regulating Hemodynamics 6. Mechanotransduction in Cardiovascular Development and Regeneration: A Zebrafish Model for Genetic Manipulation 7. Mechanosensitive microRNAs in Health and Disease 8. Mechanotransduction to the Cell Nucleus 9. Computation of Congenital Heart Disease: A Sheep Model 10. Integrating Light-Sheet Imaging and Shear Stress-Mediated Notch Signaling to Elucidate Cardiac Trabeculation for Contractile Function