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Selected Papers of Frederick Sanger
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Artikel-Nr:
9789810224301
Veröffentl:
1996
Einband:
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Erscheinungsdatum:
01.08.1996
Seiten:
678
Autor:
Frederick Sanger
Gewicht:
1451 g
Format:
260x183x41 mm
Sprache:
Englisch
Beschreibung:
This important volume is mainly concerned with the development of methods for "sequencing" - that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences.
Proteins (19 papers, from 1945 to 1961); RNA (eight papers, from 1964 to 1972); DNA (21 papers, fom 1973 to 1988).