Aminoacyl-tRNA Synthetases in Biology and Medicine

Aminoacyl-tRNA Synthetases in Biology and Medicine
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Artikel-Nr:
9789401787000
Veröffentl:
2014
Einband:
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Erscheinungsdatum:
13.05.2014
Seiten:
360
Autor:
Sunghoon Kim
Gewicht:
705 g
Format:
241x160x25 mm
Serie:
344, Topics in Current Chemistry
Sprache:
Englisch
Beschreibung:

1983-1986 Researcher, Genetic Eng. Center, KAIST, Korea
1991-1994 Post-doc, MIT, USA
1993-1994 Senior Scientist, Cubist Pharmaceuticals, USA
1994-2001 Associate Professor, Sung Kyun Kwan University, Korea
2001-present Professor, College of Pharmacy, Graduate Program in Bioinformatics , Genetic Engineering, Cancer Biology, Seoul National Univ.
1998-present Director, Center for Medicinal Protein Network and Systems Biology, Seoul National University
2008- Director, Information Center of Bio-pharmacological Network
2008- Director, Integrated Bioscience and Biotechnology Institute
This book will focus on new molecular interactions and novel activities and the associated diseases that have been recently discovered from the studies of eukaryotic and mammalian aminoacyl-tRNA synthetases. In addition, the potential applications of ARS researches in biotechnology and medicine will be addressed.
Will attract broad readership from basic life science to biotechnology and medical community
Catalysis.- Emergence and Evolution.- Architecture.- Protein-protein Interactions and Multicomponent Complexes.- Interactions with RNAs.- Secretion and Circulation.- Regulatory Roles.- Neural Diseases.- Cancer.- Immune Diseases.- Pathologic Implications of Mitochondrial tRNA Synthetases .- Infectious Diseases.- Reprogramming of Genetic Code.- Novel functions of tRNAs.- Perspectives for Systems and Synthetic Bio-Medicine.

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