Basic and Applied Aspects

Animal cell technology is a growing discipline of cell biology which aims not only to understand the structure, function and behavior of differentiated animal cells, but also to ascertain their ability to be used for industrial and medical purposes. Some of the major goals of animal cell technology include: the clonal expansion of differentiated cells, the optimization of their culture conditions, modulation of their ability for the production of medically and pharmaceutically important proteins and the application of animal cells to gene therapy, artificial organs and functional foods. This volume gives the readers a complete review of the present state-of-the-art research in Japan and other countries where this field is well advanced. The Proceedings will be useful to cell biologists, biochemists, molecular biologists, immunologists, biochemical engineers and to those working in either academic environments or in the biotechnology and pharmacy industries related to animal cell culture.

Animal cell technology is a growing discipline of cell biology which aims not only to understand the structure, function and behavior of differentiated animal cells, but also to ascertain their ability to be used for industrial and medical purposes. Some of the major goals of animal cell technology include: the clonal expansion of differentiated cells, the optimization of their culture conditions, modulation of their ability for the production of medically and pharmaceutically important proteins and the application of animal cells to gene therapy, artificial organs and functional foods. This volume gives the readers a complete review of the present state-of-the-art research in Japan and other countries where this field is well advanced. The Proceedings will be useful to cell biologists, biochemists, molecular biologists, immunologists, biochemical engineers and to those working in either academic environments or in the biotechnology and pharmacy industries related to animal cell culture.

Preface. Purification Of Hepatoblasts From Fetal Mouse Livers By Using A Temperature-Reversible Gelation Polymer And Heir Application In Regenerative Medicine. Computer Aided Rational Design Of Biochemical Systems. Dna Microarray In Nutrigenomics And Cancer Prevention Research: Elucidating Molecular Signatures Of Cancer Preventive Phytochemicals. Dna Microarray Technology Evaluation Of Effect Of Dietary Intake Of Crude Rice Glycosphingolipids In Mice. Integrated Pathway Analysis Of Genome-Wide Expression Changes Associated With Serum-Free Suspension Adaptation Of An Antibody-Producing Chinese Hamster Ovary (Cho) Cell Line. Affordable Mab By Ensuring Low Cog. Evaluation Of Neurotoxicity Of Environmental Chemicals Using Neural Stem Cells And Neuroblastoma Cells. Integration Of Endothelial Cell-Covered Hepatocyte Spheroids For Construction Of Vascularized Liver Tissue. Characterization Of Cell-Sized Vesicles Induced From Human Lymphoid Cell Lines. Dendrimer-Immobilized Culture Surface As A Tool To Promote Aggregate Formation Of Anchorage-Dependent Cells. Advantage Of Alagln As An Additive To Cell Culture Medium. Supplementation Of Phosphatidylcholine Protects The Hybridoma Cells From Apoptosis Induced By Serum Withdrawal. Monoclonal Antibody Productivity Of Hybridoma Cells Under Active Hypothermic Growth Condition.