Resistance of Salmonella to antimicrobials at the MRL in Bamako

Aly Mallé, pharmacist living in Bamako, Mali.

The retro prospective study, performed at the MRL, focused on germs isolated from samples likely to contain enterobacteria and more specifically Salmonella, from January 2015 to December 2017. Antibiotic susceptibility was determined by the Muller-Hinton agar diffusion technique and with the Vitek 2 Compact and the Mini Api automata. During the study period, a total of 739 gram-negative bacilli strains were isolated from all specimens received at the MRL Bacteriology Laboratory. Enterobacteriaceae represented 93.97% of all isolated germs or 693 strains. Salmonella spp. represented 7.31% or 54 strains, the majority of which came from stool samples (37) and blood cultures (11). The highest rates of resistance determined were to quinolones, nalidixic acid (31.91%), aminoglycosides (tobramycin 20.98%), beta-lactams (amoxicillin 8.51%) and 13.20% to co-trimoxazole. We isolated five strains of Salmonella multi-resistant to the tested antibiotics.