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Host-guest interactions between a drug and cyclodextrin
Inclusion complex formation and solution behavior
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Artikel-Nr:
9786202010283
Veröffentl:
2017
Einband:
Paperback
Erscheinungsdatum:
14.08.2017
Seiten:
56
Autor:
Abhijit Sarkar
Gewicht:
102 g
Format:
220x150x4 mm
Sprache:
Englisch
Beschreibung:
Abhijit Sarkar by profession an engineer and a researcher in the Department of Chemistry, University of North Bengal. He has published 2 books and 15 research articles in different reputed journals.Dr. Biswajit Sinha is an assistant professor in the Department of Chemistry, University of North Bengal. He has authored over 60 articles and 3 books.
The effectiveness of a drug depends on its bioavailability. The general reason of low oral bioavailability is due to low solubility of drug molecules. To get, required pharmacological action it is important to have a desired concentration of drug in the solution, for which solubility is the important factor. Cyclodextrins have the ability to solubilize hydrophobic drugs which have pharmaceutical applications and crosslink to form polymers used for drug delivery. It is therefore interesting to observe the physico-chemical interactions between the drug molecule and the carrier molecule in aqueous media.