Preparation and Evaluation of New Pyrazolo[1,5a]pyrimidine Derivatives

Preparation and Evaluation of New Pyrazolo[1,5a]pyrimidine Derivatives
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Pyrazolo[1,5-a]pyrimidines: Preparation, Antitumor & Spectral Analysis
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Artikel-Nr:
9786138925224
Veröffentl:
2020
Einband:
Paperback
Erscheinungsdatum:
06.03.2020
Seiten:
100
Autor:
Ashraf Sayed Hassan Mohamed
Gewicht:
167 g
Format:
220x150x6 mm
Sprache:
Englisch
Beschreibung:

Hassan Mohamed, Ashraf Sayed
Dr. Ashraf Sayed Hassan and Dr. Nesrin Mahmoud Morsy Mohamed are an Associate Professors and Dr.Taghrid Shoukry Mohamed Hafez is an Emeritus Professor. They are working at Organometallic and Organometalloid Chemistry Department, Chemical Industries Research Division, National Research Centre, Cairo, Egypt. They are interested in Organic Chemistry.
Exploring novel classes of antitumor agents is an excellent approach to treat cancer diseases, which is responsible for major deaths worldwide. Pyrazolo[1,5-a]pyrimidine derivatives occupy a unique place in medicinal chemistry due to its various pharmacological activities. Besides, pyrazolo[1,5-a]pyrimidine derivatives are purine analogue of particular significance in medicinal chemistry due to their broad scope of remarkable antitumor activities. In this context, a new series of pyrazolo[1,5-a]pyrimidine derivatives were synthesized, characterized by their spectral data and screened for their antitumor activities.

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