Bücher online kaufen
Novel molecular targets for genistein in prostate cancer cells
Paperback
Print on Demand | Lieferzeit: Print on Demand - Lieferbar innerhalb von 3-5 Werktagen I
Artikel-Nr:
9783838338842
Veröffentl:
2010
Einband:
Paperback
Erscheinungsdatum:
15.01.2010
Seiten:
100
Autor:
Kendra Merchant
Gewicht:
167 g
Format:
220x150x6 mm
Sprache:
Englisch
Beschreibung:
Kendra nació en St. Andrew, Jamaica, donde obtuvo su licenciatura en química y bioquímica. En 2005, se trasladó a los Estados Unidos para cursar una maestría en biología en la Universidad Atlántica de Florida y luego continuó con su doctorado. Actualmente es profesora adjunta del programa de ciencias biomédicas para graduados de la Universidad de Barry.
Genistein is a major isoflavone constituent of soy that has been shown to inhibit growth proliferation and induce apoptosis in cancer cells. The mechanism of genistein-induced cell death and potential molecular targets for genistein in LNCaP prostate cancer cells was investigated using several techniques. The chemosensitivity of genistein towards prostate cancer cells was investigated using the ATP and MTS assays and apoptosis induction was determined using apoptosis and caspase assays. Several molecular targets were also identified using cDNA microarray and RT-PCR analysis.