Diagnostics of Endocrine Function in Children and Adolescents

A Karger 'Publishing Highlights 1890-2015' title A multitude of new developments, not only in the rapidly advancing field of molecular genetics and steroid metabolism but in all traditional areas of pediatric endocrinology, have influenced the diagnostic approach in children and adolescents with endocrine disorders, thus warranting this 4th, revised and extended edition of 'Diagnostics of Endocrine Function in Children and Adolescents'. Several chapters have been revised completely and all have been thoroughly updated. In addition, new chapters dealing with the muscle-bone unit and bone metabolism have also been incorporated. The original format of the chapters, which are a combination of in-depth discussion of the diagnostic process, practical conclusions and expert advice based on extensive experience, was maintained. Easy-to-use tables and figures allow for quick reference. Flowcharts of possible diagnostic pathways lead to the most frequent diagnoses. Presenting a broad range of diagnostic approaches, test procedures, and normative data required for establishing diagnoses for a broad spectrum of endocrine disorders, this book is an indispensable reference tool not only for endocrinologists and pediatricians but also for professionals in other specialties seeking evidence-based, rapid diagnostic solutions as the basis of advice and therapy for their patients.

Preface: Ranke, M.B.; Mullis, P.-E.; Laboratory Measurements of Hormones and Related Biomarkers: Technologies, Quality Management and Validation: Elmlinger, M.W.; Molecular Genetics and Bioinformatics Methods for Diagnosis of Endocrine Disorders: Pandey, A.V.; Mullis, P.E.; Sonographic Measurement of Endocrine Tissue: Haber, H.P.; Neu, A.; In vivo Diagnostic Methods of Imaging and Testing of Endocrine Function with Radionuclides: Reiners, C.; Farahati, J.; Lassmann, M.; Diagnostic Tests of Thyroid Function in Children and Adolescents: Krude, H.; Gruters Berlin, A.; Growth Hormone Deficiency: Diagnostic Principles and Practice: Ranke, M.B.; Methods of Evaluating Spontaneous Growth Hormone Secretion: Albertsson-Wikland, K.; Rosberg, S.; Insulin-Like Growth Factors and Their Binding Proteins: Blum, W.F.; Bottcher, C.; Wudy, S.A.; Diagnosis of Growth Hormone Excess and Hyperprolactinemia: Riedl, S.; Frisch, H.; Testing Water Regulation: Czernichow, P.; Polak, M.; Diagnostic Investigations in Inherited Endocrine Disorders of Sodium Regulation: Ferrari, P.; Bianchetti, M.G.; Investigation of Calcium Disorders in Children: Perry, L.; Allgrove, J.; Hyperinsulinism, Neonatal Hypoglycemia, New Mechanisms: Valayannopoulos, V.; de Lonlay, P.; Polak, M.; Hypoglycaemia in Infants and Children: Hussain, K.; Insulin Resistance in Childhood and Adolescence: Ehehalt, S.; Neu, A.; Endocrine Function of the Testis: Holterhus, P.-M.; Honour, J.W.; Savage, M.O.; Normal Ovarian Function and Assessment of Ovarian Reserve in Children and Young People: Johnston, R.J.; Wallace, W.H.B.; Assessing the Function of the Human Adrenal Cortex: Fluck, C.E.; Mass Spectrometry in the Diagnosis of Steroid-Related Disorders: Clinical Applications: Wudy, S.A.; Hartmann, M.F.; Assessing Endocrine Function in the Newborn Baby: Ogilvy-Stuart, A.L.; Bone Metabolites: Crofton, P.M.; Quantification of Densitometric Bone Parameters and Muscle Function: Schoenau, E.; Fricke O.; Body Composition Assessment in Children and Adolescents: Wells, J.C.K.; Effect of Body Weight on Endocrine Parameters and Fat Hormones: Wabitsch, M.; Reinehr, T.; Fischer-Posovszky, P.; Diagnostics: Appendix A: Ranke, M.B.; Appendix B: Ranke, M.B.; Author Index; Subject Index.