Obesity and Metabolism

It has become increasingly difficult to keep up with the growing body of literature on the genetics, metabolic phenotype and treatment of obesity. This volume brings together an array of chapters from many of the foremost authorities and researchers in this area. Key advances in the genetics of obesity are summarized and the effects of obesity in pregnancy, childhood and old age explored. By scrutinizing the hormones and enzymes most recently implicated in the development, maintenance and consequences of obesity, the biochemical and physiological background of the abnormal metabolism of obesity is mapped out. Furthermore, a practical update on clinical approach and treatment of obesity is offered. Finally, the social aspects of obesity and the view of the obese body in art throughout the centuries are reflected. A valuable overview of causes, metabolic disturbances and treatment options, this volume will appeal to those with an interest in clinical as well as pathophysiological and genetic aspects of obesity. Furthermore, it will provide useful reading for scientists and students who would like to broaden and update their knowledge in this area.

Exklusives Verkaufsrecht für: Gesamte Welt.

Foreword: Grossman, A.B.; Preface: Korbonits, M.; Monogenic Human Obesity: Farooqi, I.S.; Polygenic Contribution to Obesity: Genome-Wide Strategies Reveal New Targets: Korner, A.; Kiess, W.; Stumvoll, M.; Kovacs, P.; Genetic Obesity Syndromes: Goldstone, A.P.; Beales, P.L.; Fetal and Neonatal Pathways to Obesity: Gluckman, P.D.; Hanson, M.A.; Beedle, A.S.; Raubenheimer, D.; Developmental Origins of Obesity and the Metabolic Syndrome: The Role of Maternal Obesity: Armitage, J.A.; Poston, L.; Taylor, P.D.; Childhood Obesity: Sabin, M.A.; Shield, J.P.H.; Obesity in Old Age: McPhee Chapman, I.; Models of 'Obesity' in Large Animals and Birds: Clarke, I.J.; The [beta]-Cell in Type 2 Diabetes and in Obesity: Rutter, G.A.; Parton, L.E.; Role of the Endocannabinoid System in Energy Balance Regulation and Obesity: Cota, D.; 11[beta]-Hydroxysteroid Dehydrogenase Type 1 and Obesity: Morton, N.M.; Seckl, J.R.; Gut and Hormones and Obesity: Wren, A.M.; Adipokines in Obesity: Ahima, R.S.; Osei, S.Y.; The Role of AMP-Activated Protein Kinase in Obesity: Kola, B.; Grossman, A.B.; Korbonits, M.; Classical Endocrine Diseases Causing Obesity: Weaver, J.U.; Emerging Concepts in the Medical and Surgical Treatment of Obesity: Aylwin, S.; Al-Zaman, Y.; The Sociology of Obesity: Rosengren, A.; Lissner, L.; Obesity in Art - A Brief Overview: Woodhouse, R.; Author Index; Subject Index.