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Cancer Bioassays: A Statistical Approach
Statistical Methods for the Cancer problem
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Artikel-Nr:
9783659294518
Einband:
.
Seiten:
116
Autor:
Christos P. Kitsos
Format:
220x150x0 mm
Sprache:
Englisch
Beschreibung:
Prof C. P. Kitsos graduated from the University of Athens in 1973 (MATH). He received his MA from Univ. of New Brunswick, Canada, and PhD from Univ. of Glasgow, UK in Statistics. He is a Prof. at the Technological Educational Institute of Athens, Greece. He is an author of 36 papers at journals, 84 at proceedings volumes and 15 books in Statistics.
The aim of this monograph is to discuss the statistical bioassay of experimental carcinogenesis. The interest in the of the cancer risk assessment has led to various statistical lines of thought, due to different intrinsic biological background and supported by the appropriate statistical analysis. The biological insight (cell proliferation, mechanism of inhibition in mutagenesis and carcinogenesis) of a cancer risk assessment has not been tackled. Emphasis was given to the statistical models considered in the literature in the area of experimental carcinogenesis as well as on the dose dependent models. Moreover, an optimal experimental design approach is discussed, for evaluating the percentiles of a distribution.