Aspects of Lyme Borreliosis

Klaus Weber leitet als Regierungsdirektor bei der Landesdirektion Chemnitz das Referat Verkehrsrecht . Zahlreiche Veröffentlichungen in juristischen Zeitschriften zum Allgemeinen Verwaltungsrecht, Polizeirecht, Europarecht und auch Verwaltungsvollstreckungsrecht belegen seine Fachkompetenz. Er war von 1992 bis 2006 Arbeitsgemeinschaftsleiter für Rechtsreferendare und ist seit über 10 Jahren Lehrbeauftragter an der Fachhochschule der Sächsischen Verwaltung in Meißen und bei der Verwaltungsakademie in Chemnitz.

Aspects of Lyme Borreliosis is a comprehensive scientificpresentation of virtually all aspects of lyme borreliosis.It starts with a concise history of lyme borreliosis and itscausative agent, Borrelia burgdorferi. The morphological andbiological characteristics of B. burgdorferi are presented,followed by outlines on the ecology and histopathology ofLB.The various aspects of the clinical manifestations of LBare systematically dealt with, starting with a clinicaloverview. A special chapter covers the microbiologicaldiagnosis. After a presentation on the susceptibility of B.burgdorferi in vitro and in animals against a great varietyof antibiotics, a thorough discussion on the treatment of LBincluding criticalremarks follows. The book closes with achapter on the epidemiology of LB.

I History.- 1 History of Lyme Borreliosis in Europe.- 2 The Historical Road to the Discovery of Borrelia burgdorferi.- II Characteristics of Borrelia burgdorfer.- 3 Ultrastructure of Borrelia burgdorferi.- 4 Biology of Borrelia burgdorferi.- III Ecology and Histopathology of Lyme Borreliosis.- 5 The Ecology of Lyme Borreliosis in Europe.- 6 Histopathology of Human Lyme Borreliosis.- IV Clinical Features of Lyme Borreliosis.- 7 Clinical Overview.- 8 Erythema Migrans and Early Signs and Symptoms.- 9 Borrelial Lymphocytoma.- 10 Lyme Carditis.- 11 Early Neurological Involvement (Bannwarth's Syndrome).- 12 Joint Manifestations.- 13 Myalgia, Myositis, and Fasciitis.- 14 Acrodermatitis Chronica Atrophicans.- 15 Chronic Central Nervous System Involvement.- 16 Chronic Peripheral Neuropathy.- 17 Lyme Borreliosis in Childhood and Pregnancy.- 18 Localized Scleroderma and Liehen Sclerosus et Atrophicus: Manifestations of a Borrelia burgdorferi Infection?.- 19 Ocular Manifestations.- 20 Borrelial Dermatomyositis-like Syndrome.- V Microbiological Diagnosis of Lyme Borreliosis.- 21 Microbiological Diagnosis of Lyme Borreliosis.- VI Therapy of Lyme Borreliosis.- 22 Antibiotic Susceptibility of Borrelia burgdorferi. In Vitro and In Vivo.- 23 Therapy of Cutaneous Manifestations.- 24 Therapy of Lyme Neuroborreliosis.- 25 Therapy of Joint Manifestations.- 26 Therapy of Lyme Carditis.- 27 Therapy of Tick Bite.- 28 Critical Remarks on Antibiotic Therapy.- VII Epidemiology of Lyme Borreliosis.- 29 Epidemiology of Lyme Borreliosis.- Color plates I-IV.