Adenovirus Epithelial Keratitis and Thygeson’s Superficial Punctate Keratitis

The two very different diseases examined here—the former common and contagious, the latter rare and noninfectious—have confusingly similar symptoms. The book’s high-magnification images and case reports help clinicians distinguish between the two.

Despite differences in frequency, causation, and infectivity, adenovirus epithelial keratitis and Thygeson's superficial punctate keratitis (TSPK) are often confused in clinical practice owing to the similarity between adenovirus epithelial infiltrates and ‘coarse’ epithelial TSPK lesions. This book presents the morphological features, dynamics, and sequelae of adenovirus and Thygeson's keratitides captured at high magnification in the living human cornea. It thereby fills the existing void between conventional photographs and slit-lamp observations. Case reports demonstrate the importance of patient history in differential diagnosis, illustrate the need for familiarity with early manifestations of adenovirus infections, and assist in the diagnosis of rare variants of TSPK. Furthermore, the detailed observations on the natural course of the diseases ensure that the book will serve not only as a diagnostic tool but also as a reference when evaluating the effects of potential new treatments.

Adenovirus Epithelial Keratitis: The Morphology of Adenovirus Epithelial Keratitis.- Adenovirus Type 8 Epithelial Keratitis, Accompanying Signs and Sequelae.- Adenovirus Epithelial Keratitis Caused by Various Serotypes.- The Development of Subepithelial Infiltrates - a Sequence of Events. Thygeson’s Superficial Punctate Keratitis: The Morphology of Thygeson’s Superficial Punctate Keratitis (TSPK).- Typical Cases of Thygeson’s Superficial Punctate Keratitis.