Doping in Sports

This book covers the pharmacological basis for a possible performance enhancement in competitive sport through the administration of prohibited substances and methods as well as the analytical disclosure of such practices.

History of Doping and Doping Control.- Biochemical and Physiological Aspects of Endogenous Androgens.- Phase-II Metabolism of Androgens and Its Relevance for Doping Control Analysis.- Detecting the Administration of Endogenous Anabolic Androgenic Steroids.- Synthetic Anabolic Agents: Steroids and Nonsteroidal Selective Androgen Receptor Modulators.- Nandrolone: A Multi-Faceted Doping Agent.- Designer Steroids.- Growth Hormone.- Mass Spectrometry-Based Analysis of IGF-1 and hGH.- Insulin.- ?-Adrenergic Stimulation.- Erythropoietin and Analogs.- Blood Transfusion in Sports.- The Athlete's Biological Passport and Indirect Markers of Blood Doping.- Masking and Manipulation.- Hormonal Growth Promoting Agents in Food Producing Animals.- Some Aspects of Doping and Medication Control in Equine Sports.- Androgenic Anabolic Steroid Abuse and the Cardiovascular System.- Side Effects of Anabolic Androgenic Steroids: Pathological Findings and Structure-Activity Relationships.- Gene Doping.- Science and the Rules Governing Anti-Doping Violations.