Anion Coordination Chemistry

Building on the pioneering work in supramolecular chemistry from the last 20 years or so, this monograph addresses new and recent approaches to anion coordination chemistry. Synthesis of receptors, biological receptors and metallareceptors, the energetics of anion binding, molecular structures of anion complexes, sensing devices are presented and computational studies addressed to aid with the understanding of the different driving forces responsible for anion complexation. The reader is promised an actual picture of the state of the art for this exciting and constantly evolving field of supramolecular anion coordination chemistry. The topics range from ion channels to selective sensors, making it attractive to all researchers and PhD students with an interest in supramolecular chemistry.

Building on the pioneering work in supramolecular chemistry from the last 20 years or so, this monograph addresses new and recentapproaches to anion coordination chemistry. Synthesis of receptors, biological receptors and metallareceptors, the energetics of anion binding, molecular structures of anion complexes, sensing devices are presented and computational studies addressed to aid with the understanding of the different driving forces responsible for anion complexation. The reader is promised an actual picture of the state of the art for this exciting and constantly evolving field of supramolecular anion coordination chemistry. The topics range from ion channels to selectivesensors, making it attractive to all researchers and PhD students with an interest in supramolecular chemistry.

PrefaceASPECTS OF ANION COORDINATION FROM HISTORICAL PERSPECTIVESIntroductionHalide and Pseudohalide AnionsOxoanionsPhosphate and Polyphosphate AnionsCarboxylate Anions and Amino AcidsAnionic Complexes: Supercomplex FormationNucleotidesFinal NotesTHERMODYNAMIC ASPECTS OF ANION COORDINATIONIntroductionParameters Determining the Stability of Anion ComplexesMolecular Recognition and SelectivityEnthalpic and Entropic Contributions in Anion CoordinationSTRUCTURAL ASPECTS OF ANION COORDINATION CHEMISTRYIntroductionBasic Concepts of Anion Coordination ChemistryClasses of Anion HostsAcyclesMonocyclesCryptandsTransition-Metal-Assisted LigandsLewis Acid LigandsConclusionSYNTHETIC STRATEGIESIntroductionDesign and Synthesis of Polyamine-Based Receptors for AnionsDesign and Synthesis of Amide ReceptorsTEMPLATE SYNTHESISIntroductory RemarksMacrocyclic SystemsBowl-Shaped SystemsCapsule, Cage, and Tube-Shaped SystemsCircular Helicates and meso-HelicatesMechanically Linked SystemsConcluding RemarksANION-PI INTERACTIONS IN MOLECULAR RECOGNITIONIntroductionPhysical Nature of the InteractionEnergetic and Geometric Features of the Interaction Depending on the Host (Aromatic Moieties) and the Guest (Anions)Influence of Other Noncovalent Interactions on the Anion-Pi InteractionExperimental Examples of Anion-Pi Interactions in the Solid State and in SolutionConcluding RemarksRECEPTORS FOR BIOLOGICALLY RELEVANT ANIONSIntroductionPhosphate ReceptorsCarboxylate ReceptorsConclusionSYNTHETIC AMPHIPHILIC PEPTIDES THAT SELF-ASSEMBLE TO MEMBRANE-ACTIVE ANION TRANSPORTSIntroduction and BackgroundBiomedical Importance of Chloride ChannelsThe Development of Synthetic Chloride ChannelsApproaches to Synthetic Chloride ChannelsThe Development of Amphiphilic Peptides as Anion ChannelsStructural Variations in the SAT Modular ElementsConclusionsANION SENSING BY FLUORESCENCE QUENCHING OR REVIVALIntroductionAnion Recognition by Dynamic and Static Quenching of FluorescenceFluorescent Sensors Based on Anthracene and on a Polyamine FrameworkTurning on Fluorescence with the Indicator Displacement Approach