Multi-Step Enzyme Catalysis

The first comprehensive coverage of this unique and interdisciplinary field provides a complete overview, covering such topics as chemoenzymatic synthesis, microbial production of DNA building blocks, asymmetric transformations by coupled enzymes and much more. By combining enzymatic and synthetic organic steps, the use of multi-enzyme complexes and other techniques opens the door to reactions hitherto unknown, making this monograph of great interest to biochemists, organic chemists, and chemists working with/on organometallics, as well as catalytic chemists, biotechnologists, and those working in the pharmaceutical and fine chemical industries.

The first comprehensive coverage of this unique and interdisciplinary field provides a complete overview, covering such topics as chemoenzymatic synthesis, microbial production of DNA building blocks, asymmetric transformations by coupled enzymes and much more. By combining enzymatic and synthetic organic steps, the use of multi-enzyme complexes and other techniques opens the door to reactions hitherto unknown, making this monograph of great interest to biochemists, organic chemists, and chemists working with/on organometallics, as well as catalytic chemists, biotechnologists, and those working in the pharmaceutical and fine chemical industries.

Multi-Enzyme Synthesis of GlycoconjugatesMultimodular Synthases as Tools of the Synthetic ChemistModifying the Glycosilation Pattern in Microorganisms by Combinatorial BiosynthesisChemoenzymatic Routes to Enantiomerically Pure Amines and AminoacidsAsymmetric Transformations by Couples Enzymes and Metal CatalysisEngineering Novel Biosynthetic Pathways to Produce New Chemical CompoundsBiocatalysis and Chemical Catalysis for the Synthesis of Intermediates of Pharmaceutical InterestOxidizing Enzymes into Multi-Enzyme Biotransformation ProcessesThe Role of Host-Intrinsic Enzyme Activities in Recombinant Whole-Cells Catalyzed ProcessesMicrobial Production of DNA Building BlocksEnzyme Initiation of Asymmetric Cascade-ReactionsThe System of Biotransformations Approach for Multi-Step ProcessesChemoenzymatic Synthesis of Homogeneous GlycoproteinAldolases Catalyzed C-C Bond Formation in the Core of Multi-Step Processes