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Nitric Oxide Donors
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For Pharmaceutical and Biological Applications
E-Book
Sofort lieferbar | Lieferzeit: Sofort lieferbar
Artikel-Nr:
9783527603848
Veröffentl:
2006
Einband:
E-Book
Seiten:
407
Autor:
Peng George Wang
eBook Typ:
PDF
eBook Format:
Reflowable E-Book
Kopierschutz:
Adobe DRM [Hard-DRM]
Sprache:
Englisch
Beschreibung:
Nitric oxide is a highly potent regulatory molecule with great pharmaceutical potential. This handbook fills a real gap in combining the chemistry of nitric oxide releasing substances with their practical applications in biology and drug design. It covers all classes of nitric oxide donors, from organic nitrates to nitroso compounds, guanidines and metal-NO complexes. In addition to a detailed treatment of the chemistry of NO donors, numerous examples of successful diagnostic and pharmacological applications are discussed, as well as further therapeutic targets for these substances.
Nitric oxide is a highly potent regulatory molecule with great pharmaceutical potential. This handbook fills a real gap in combining the chemistry of nitric oxide releasing substances with their practical applications in biology and drug design. It covers all classes of nitric oxide donors, from organic nitrates to nitroso compounds, guanidines and metal-NO complexes.In addition to a detailed treatment of the chemistry of NO donors, numerous examples of successful diagnostic and pharmacological applications are discussed, as well as further therapeutic targets for these substances.
CHEMISTRY OF NO DONORSNO and NO DonorsOrganic Nitrates and NitritesN-Nitroso CompoundsThe Role of S-Nitrosothiols in the Biological MilieuMetal-NO ComplexesNO Releasing HeterocyclesC-nitroso compounds, Oximes, N-hydroxyguanidines and N-hydroxyureasNO DONORS' APPLICATIONS IN BIOLOGICAL RESEARCHVasodilators for Biological ResearchNO Donors as Antiplatelet AgentsControl of NO ProductionCLINICAL APPLICATIONS OF NO DONORSNO Donors in Cardiovascular DiseaseNO Donors as Anti-Platelet Agents for thromboembolic disordersNO and Gene RegulationNO and Central Nervous System Diseases