Victor R. Preedy (B.Sc., Ph.D., D.Sc., FRSB, FRSPH, FRCPath, FRSC) is a senior member of King's College London, where he is also Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy graduated in 1974 with an Honors Degree in Biology and Physiology with Pharmacology. He gained his University of London Ph.D. in
1981. In 1992, he received his Membership of the Royal College of Pathologists, and in 1993 he gained his second doctoral degree for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then, he has been elected as Fellow to the Royal Society for the Promotion of Health (2004) and the Royal Institute of Public Health (2004). In 2009, Professor Preedy became Fellow of the Royal Society for Public Health and, in 2012, FellowThis multivolume reference work addresses the fact that the well being of humankind is predicated not only on individuals receiving adequate nutrition but also on their genetic makeup. The work includes more than 100 chapters organized in the following major sections: Introduction and Overview; Epigenetics of Organs and Diseases in Relation to Diet and Nutrition; Detailed Processes in Epigenetics of Diet and Nutrition; Modulating Epigenetics with Diet and Nutrition; and Practical Techniques. While it is well known that genes may encode proteins responsible for structural and dynamic components, there is an increasing body of evidence to suggest that nutrition itself may alter the way in which genes are expressed via the process of epigenetics. This is where chemically imposed alteration in the DNA sequence occurs or where the functional expression of DNA is modulated. This may include changes in DNA methylation, non-coding RNA, chromatin, histone acetylation or methylation, and genomic imprinting. Knowledge regarding the number of dietary components that impact on epigenetic processes is increasing almost daily. Marshalling all the information on the complex relationships between diet, nutrition, and epigenetic processes is somewhat difficult due to the wide myriad of material. It is for this reason that the present work has been compiled.
Nervous system.- Development and ageing.- Cancers.- Caloric and dietary restriction.- Detailed processes in epigenetics of diet and nutrition.-Modifications of DNA via methylation.- Modifications of histones.- Modifications of non-coding RNAs.- DNA repair.- Modulating epigenetics with diet and nutrition.- General treatments and strategies.- Vitamins.- Minerals.- Specific foods and nutrients.- Nutritional toxicology.- Practical techniques.