Der Artikel wird am Ende des Bestellprozesses zum Download zur Verfügung gestellt.

Handbook of Meningococcal Disease Management

 eBook
Sofort lieferbar | Lieferzeit: Sofort lieferbar I
ISBN-13:
9783319281193
Einband:
eBook
Seiten:
111
Autor:
Ian Feavers
eBook Typ:
PDF
eBook Format:
eBook
Kopierschutz:
Digital Watermark [Social-DRM]
Sprache:
Englisch
Beschreibung:

This concise pocketbook will provide readers with an overview and background of meningococcal disease, treatment options and emerging therapies, and methods of prevention. The book was originally commissioned due to recent developments in vaccinations to prevent meningococcal disease. This book reviews the disease progression and associated risk factors; its pathogenesis and diagnosis; methods of treatment and prevention, both current and emerging; and the future directions of meningococcal disease management. The book is ideal for busy healthcare professionals, as it covers all aspects of the disease and its treatment in a condensed and manageable format, whilst including the most up-to-date treatment guidelines and algorithms.
1. Introduction and epidemiology of meningococcal disease


Neisseria meningitidis 


Disease surveillance 


Case fatality and sequelae 


Epidemiology of meningococcal disease 


Capsular groups causing disease 


Current issues 


Summary points 


References 







2. Carriage and transmission of Neisseria meningitidis


Introduction 


Detecting the carrier state


The natural history of meningococcal carriage


Epidemiology of carriage


Other Neisseria species


Effect of vaccination on carriage


Summary points


References 







3. Pathogenesis of invasive disease


Introduction


Transmission, adaptation, and penetration to the circulation


Neisseria meningitidis and intravascular survival


Meningococcemia: a disease of the endothelial cells


Pathophysiological characteristics of clinical presentations of meningococcal disease




The immune response


Summary points


References








4. Diagnosis of meningococcal disease


Introduction


Conventional diagnosis


Molecular diagnosis 


Typing of
Neisseria meningitidis


Summary and future outlook


References








5. Clinical aspects of meningococcal disease


Introduction 


Clinical spectrum of disease


Symptoms of disease


Disease outcomes and prognosis 


Raising awareness of disease 


Genetic factors 


Summary points 


References








6. Treatment of meningococcal disease


Introduction


Shock


Raised intracranial pressure


Antibiotic therapy


Adjunctive therapies 


Where to manage children with meningococcal disease? 


Summary points 


References







7. Prevention of meningococcal disease through vaccination


Introduction 


Polysaccharide vaccines 


Protein-polysaccharide conjugate vaccines 


Production and quality control of polysaccharide and conjugate vaccines


Immunological correlates of protection 


Capsular group B vaccines 


Summary points 


References







Appendix 


Management of bacterial meningitis in children and young people 




Management of meningococcal disease in children and young people




Early management of suspected bacterial meningitis and meningococcal septicaemia in immunocompetent adults