Multimodality Management of Borderline Resectable Pancreatic Cancer

This volume provides the most comprehensive coverage of clinical management of borderline resectable pancreatic cancer available. Authored by leaders in the field, the book focuses on current clinical management of this disease stage, the importance of multimodality treatment algorithms, and an interdisciplinary approach to care. Surgical chapters are well-illustrated to provide surgeons and surgical trainees with important technical pearls. Clinical trials and trial design are also discussed.

Multimodality Management of Borderline Resectable Pancreatic Cancer is a valuable resource for gastroenterologists, medical oncologists, radiation oncologists, surgical oncologists, general surgeons, and trainees interested in the treatment of pancreatic cancer.

Part 1. Overview

1. Anatomic Definitions of Borderline Resectable Pancreatic Cancer
Rebecca A. Snyder, Alexander A. Parikh, Kamran Idress, and Nipun B. Merchant

Part 2. Staging and Pretreatment Management

2. Imaging Evaluation of Borderline Pancreatic Cancer
Kyuran Ann Choe  and Nicholas M. McDonald

3. Endoscopic Ultrasonography: Staging and Therapeutic Intervention
Girish Mishra and Rishi Pawa

4. Endoscopic and Percutaneous Biliary Drainage Procedures: Role in Preoperative Management, Diagnosis, and Palliation
Milton T. Smith
 
Part 3. Multimodal Therapy

5. Overview of Multimodality Therapy
Robert de Wilton Marsh and Marshall S. Baker
 
6. Role of Systemic Therapy
Matthew J. Reilley and Gauri Varadhachary

7. Role of Radiation Therapy
Neilayan Sen and Ross Abrams

8. Stereotactic Body Radiation Therapy as an Emerging Option for Localized Pancreatic Cancer
Rachit Kumar, Lauren M. Rosati, and Joseph M. Herman

9. Assessment of Response to Preoperative Therapy
André L. Mihaljevic and Jörg Kleeff

10. Emerging Systemic and Targeted Therapies
Trailokya Pandit and Philip A. Philip

Part 4. Surgery

11. Operative Principles in Managing Patients with Borderline Resectable Pancreas Cancer
Kaitlyn J. Kelly and Andrew M. Lowy

12. Is There a Role for Laparoscopic and/or Robotic Techniques for Borderline Resectable Tumors?
Lee M. Ocuin, Herbert J. Zeh III, and Amer H. Zureikat

13. Role and Techniques Of Vascular Resection
Mark J. Truty

14. Artery-First Approaches to Pancreaticoduodenectomy
Kyoichi Takaori and Shinji Uemoto

15. Venous Shunting Procedures for Borderline Resectable Pancreatic Cancer
Amir H. Fathi, Susan Tsai, Jeffrey E. Lee, Douglas B. Evans, and Kathleen K. Christians

16. The Role of the Appleby Operation and Arterial Resection in the Multimodality Management of Borderline Resectable Pancreatic Cancer
Ken-ichi Okada and Hiroki Yamaue

17. Surgery for Borderline Resectable Pancreatic Cancer: The Japanese Experience
Shuji Isaji, Masashi Kishiwada, and Hiroyuki Kato

18. The Role of Irreversible Electroporation and Other Ablative Techniques in Patients with Borderline Resectable Pancreatic Cancer
Robert C.G. Martin II and Rachel O’Connor

19. Surgical Approach to Borderline Resectable tumors of the Left Pancreas
Nicholas Spinelli and William Hawkins

20. Palliative Operations for Unresectable Pancreatic Cancer
Hishaam Ismael and Brian Badgwell