Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 1

Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis Vol. 1
 Broschiert (FH)
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Artikel-Nr:
9783132012912
Veröffentl:
2017
Einband:
Broschiert (FH)
Seiten:
548
Autor:
Steven Nolan
Gewicht:
1104 g
Format:
255x171x31 mm
Sprache:
Englisch
Beschreibung:

The field of N-heterocyclic carbenes, whether in transition-metal catalysis or organocatalysis, is rapidly evolving towards applications, but is also still very active on the catalyst development front. Significant advances have been made over the past two decades and the development of these reactions has dramatically improved the efficiency of organic synthesis. N-Heterocyclic carbene based catalysts are now widely applied in the area of synthesis of both natural products and therapeutic agents. "Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis" presents the most commonly used and significant metal- or non-metal-catalyzed reactions for modern organic synthesis. The basic principles and current state-of-the-art of the methods are covered. Scope, limitations, and mechanism of these reactions are discussed and key experimental procedures are included. Typical examples of target synthesis are often provided to show the utility and inspire further applications.
Volume 1 provides a detailed introduction to NHCs, with discussion of their architectures and steric and electronic properties.

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