Fine Needle Aspiration Cytology of the Breast

Gary Man-Kit Tse is Professor of Pathology at the Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong. He is the Regional Editor of Australasia for Histopathology, Section head for Diagnostic Pathology, and is on the advisory/editorial board of Acta Cytologica, Cancer Cytopathology, Journal of the American Society of Cytopathology, Modern Pathology, Pathology, Seminars in Diagnostic Pathology, and others.  He has published extensively on breast pathology, and lectures at regional and international meetings.

Dr Puay Hoon Tan is Chairman and Senior Consultant of the Division of Pathology, Singapore General Hospital, Academic Chair of the SingHealth-Duke NUS Pathology Academic Clinical Program, Professor at Duke NUS Medical School and Professor of the Department of Anatomy, Yong Loo Lin School of Medicine NUS.  She is a Standing Editorial Board Member for the 5th series of the WHO Classification of Tumours, IARC, Lyon, and an expert member for the Breast volume published in 2019.  She was a Volume Editor of the 2012 (4th series) WHO Classification of Tumours of the Breast.  She sits on the Editorial Boards of Modern Pathology, Breast Cancer Research, Pathology, Seminars in Diagnostic Pathology.  She is Associate Editor of Histopathology and the Singapore Medical Journal.  She is author of more than 400 publications, and participates regularly in regional and international meetings.

Fernando Schmitt is Professor of Pathology and Oncology at the Medical Faculty, Porto University and Director of the Molecular Pathology Unit at the Institute of Molecular Pathology and Immunology of the University of Porto. Prof Schmitt is President of the International Society of Breast Pathology and General Secretary of the International Academy of Cytology. He is Associate editor of Acta Cytologica and Diagnostic Cytopathology and member of editorial board of several journals of pathology and cytopathology. Hehas published extensively on molecular cytopathology and breast pathology, and lectures widely at regional and international meetings.

This book provides a detailed update on all aspects of fine-needle aspiration cytology of breast lesions. It will serve as an up-to-date reference and atlas on new entities in breast pathology, including classic benign and malignant lesions, in accordance with current classification schemes and staging protocols. Emphasis is placed on description of characteristic diagnostic features as well as common cytological pitfalls. Correlation of cytology with histology is achieved through cyto-histological illustrations, enabling readers to gain a good understanding of the morphologic features of various lesions. Core-needle biopsy and fine-needle aspiration cytology are compared in depth, with attention to their relative strengths and weaknesses and indications. In addition, the impact of molecular classification of breast cancers on cytologic diagnosis is explored, and the use of molecular techniques and artificial intelligence in diagnostic cytology is discussed.

Anatomy and Physiology of the Breast.- Basic Histopathology of Breast Lesions.- Aspiration Techniques.- Liquid-Based Cytology and Cell Block in Breast Lesions.- Cytolologic classification and reporting systems.- Inflammatory Lesions of the Breast.- Fibrocystic Changes and Cysts.- Fibroadenoma.- Other Fibroepithelial Lesions.- Cytology of Epithelial Proliferative Lesions and High-Grade Ductal Carcinoma In Situ.- Papillary Lesions of the Breast.- Mucinous Lesions.- Carcinoma and Variants.- other uncommon lesions.- Assessment of Axillary Nodes.- Special Ancillary Techniques : Immunohistochemistry.- Molecular Studies and novel modalities.- Comparison of Aspiration and Core Needle Biopsy.- Future Directions.