Oral Submucous Fibrosis

Saman Warnakulasuriya is Professor Emeritus at King's College London and has been Director of the WHO Collaborating Centre on Oral Cancer since 2005. He is a Past President of the British Dental Association (Metropolitan Branch). Dr. Warnakulasuriya has served on several expert working groups of the International Agency for Research on Cancer (IARC) to evaluate carcinogenicity of substances to humans. He has delivered numerous keynote lectures at international Oral Medicine, Pathology, and Oncology conferences and was on the organizing committee and co-chaired the Global Oral Cancer Forum in New York in 2016. He is a global expert on the epidemiology and risk factors on oral cancer, developed the nomenclature of oral potentially malignant disorders, and has authored more than  300 scientific articles as well as three books, including most recently the Springer book Textbook on Oral Cancer: Prevention, Diagnosis and Management. He is a member of the editorial boardsof Oral Oncology, Oral Diseases and Clinical Oral Investigations. Dr. Warnakulasuriya has received an OBE from Her Majesty the Queen for services to Medicine and was awarded the IADR's Distinguished Scientist Awards for Oral Medicine & Pathology (2015) and Global Oral Health Research (2022). He is a Fellow of King's College London.

Kannan Ranganathan MDS, MS, PhD is Professor and Consultant in the Department of Oral Pathology at the Ragas Dental College in Chennai , President, Asian Society of Oral and Maxillofacial Pathology and Secretary of the International Association of Oral Pathologists. He obtained his BDS and MDS from The Tamilnadu Government Dental College, Chennai in 1987 and 1990 respectively. He obtained his Masters in Oral pathology from the Ohio State University, Columbus, Ohio, USA in 1996 and passed the Fellowship examination of the American Academy of Oral and Maxillofacial Pathology in 1996. He obtained his PhD - on Oral Submucous Fibrosis,from The Tamilnadu Dr MGR Medical University, Chennai, in 2010. He was conferred Best Teacher Award - for perpetuating academic excellence by the Tamilnadu Dr MGR Medical University in 2011.  He was conferred the fellowship of the Indian Association of Oral and Maxillofacial Pathology (IAOMP) in 2010 and was the the President of IAOMP (2015-2016). Dr. Ranganathan is a well experienced teacher in Oral Oncology, Oral Pathology, Oral Medicine, has  around 200 publications to his credit and has contributed enormously to international literature on those topics in research publications and as editor or chapter author in textbooks.

The book presents guides to the diagnosis and management of Oral Submucous Fibrosis, and includes a concise update on the recent evidence on aetiology and aetiopathogenesis to educate the reader on the prevention of the disease. Oral Submucous Fibrosis is a potentially malignant disorder that leads to the development of oral cancer. The first part of the book is dedicated to the epidemiology, the clinical features and the classification of Oral Submucous Fibrosis and associated conditions. The aetiology of Oral Submucous Fibrosis including lifestyle and genetic factors is discussed in the second part of the book followed by two chapters on the etiopathogenesis of the disease. Readers will find clear guidance on investigative techniques and the management of Oral Submucous Fibrosis. The last part of the book considers the connection between Areca nut and the disease and outlines methods of supporting areca nut chewers on habit cessation. The book is designed to serve as a comprehensive resource and reference in the oral health domain for learners at all levels, researchers, clinicians, and public health professionals. It will be of great value for students and trainees on any graduate program in dentistry.

Chapter 1. ORAL SUBMUCOUS FIBROSIS - An Historical Perspective.- Chapter 2. Epidemiology of Oral Submucous Fibrosis: Prevalence & trends.- Chapter 3. Clinical Features - Oral Submucous Fibrosis.- Chapter 4. Associated Conditions of Oral Submucous Fibrosis.- Chapter 5. Oral submucous fibrosis in childhood.- Chapter 6. Classification Systems for Oral Submucous Fibrosis.-  Chapter 7. Malignant transformation of oral submucous fibrosis.- Chapter 8. Lifestyle factors.-  Chapter 9. Genetic aspects of Oral Submucous Fibrosis.- Chapter 10. Diet and Micronutrients.- Chapter 11. In Vivi and In Vitor Experimental Evidence.- Chapter 12.  Fibrogenic factors and molecular mechanisms.- Chapter 13. Non-invasive diagnostic techniques in oral submucous fibrosis.- Chapter 14. Pathology of Oral Submucous Fibrosis.- Chapter 15. Biomarkers in Oral Submucous Fibrosis.- Chapter 16. Medical Management of Oral Submucous Fibrosis.- Chapter 17. Curcumin as a chemopreventive agent for oral submucous fibrosis.- Chapter 18. Surgical Management of Oral Submucous Fibrosis.- Chapter 19. Areca nut addiction- Tools to assess addiction.- Chapter 20. Behavioural interventions for areca nut cessation in the prevention and management of oral submucous fibrosis.- Chapter 21. Pharmaceutical agents for areca nut cessation.- Chapter 22. World Literature - Bibliography.