Infection in Knee Replacement

This book provides an in-depth overview of the aetiology, treatment and prevention of infections following knee arthroplasty. It presents up-to-date information on available techniques and salvage procedures for complex patients with infected, total knee arthroplasty.Divided into 5 sections, this book explores biomaterials, clinical manifestations, diagnosis, treatment and prevention, including preoperative optimisation, in order to reduce knee infections.This book is a valuable reference resource for practicing orthopaedic surgeons, residents, and medical students wishing to understand the fundamental concepts in infectious disease medicine needed in current orthopaedic practice.

This book provides an in-depth overview of the aetiology, treatment and prevention of infections following knee arthroplasty. It presents up-to-date information on available techniques and salvage procedures for complex patients with infected, total knee arthroplasty.

Divided into 5 sections, this book explores biomaterials, clinical manifestations, diagnosis, treatment and prevention, including preoperative optimisation, in order to reduce knee infections.

This book is a valuable reference resource for practicing orthopaedic surgeons, residents, and medical students wishing to understand the fundamental concepts in infectious disease medicine needed in current orthopaedic practice.

Epidemiology and socioeconomic impact of infections in knee replacement .- Aetiology and pathogenesis of knee replacement infections.Biomaterials in artificial joint replacement. The role of the surface on bacteria-implant interactions.- In-vitro and in-vivo models for the study of prosthetic joint infections. Clinical manifestation. General and local symptoms. Diagnosis. Laboratory diagnosis .- Microbiological diagnosis.- Molecular analysis and histological evaluation.- Imaging.- Definitional criteria and algorithms of diagnosis. Treatment of knee replacement infections. Systemic antibiotic therapy.- Innovative pharmacological strategies.- Surgical approaches.- DAIR  .- One stage.- Two stage.- Static spacers.- Dynamic spacers.- Arthrodesis.- Outcomes.- Complications.- Resistant germs.Current evidence on prevention of knee replacement infections. Medical optimization of patient prior to surgery.- Antibiotic prophylaxis during primary and revision joint replacement.- Preoperative management.- Intraoperative management.- Dental Procedures after joint replacement.- Thromboprophylaxis and haematomas.- Antibiotic impregnated cement.- Arthroplasty following Prior septic arthritis.- Antibiotic-loaded cement in primary and revision joint replacement.- Operative Room.- Tourniquet.- Intraarticular injection prior Joint replacement.