Urinary Bladder Pathology

This book focuses on bladder cancer pathology, including primary bladder malignancies and other tumor varieties, with an emphasis on diagnostic pitfalls and clinical relevance. It also describes normal bladder histology, benign abnormalities with cancer mimickers, and cancer carcinogenesis, which are important subject matter for understanding bladder cancers, correct diagnosis, and differential diagnoses. Accurate diagnosis of bladder cancer plays a central role in daily pathology practice, clinical management, and prognosis. Advances in immunohistochemistry and molecular pathology have enhanced the accuracy of cancer pathology diagnoses. In addition to covering the anatomic and histologic features of bladder tumors, this book also reviews recent molecular and immunohistochemical advances in these areas. Recently updated clinical management information is also presented in this book.Written by experts in the field, Urinary Bladder Pathology serves as a useful resource for practicing pathologists, pathology trainees, and other health professionals who treat patients with bladder cancers.

Introduction.- Normal histology and anatomy of urinary bladder.- Flat epithelial lesion: reactive atypia, atypia of unknown significance, dysplasia and carcinoma in situ.- Papillary tumors.- Invasive urothelial carcinoma.- Variants of urothelial carcinoma.- Other types of carcinoma.- Mesenchymal tumors.- Neuroendocrine tumors.- Lymphoreticular neoplasms.- Metastatic tumors.- Cytology.- Radiologic findings.- Molecular pathology.- Surgical treatment.- Medical treatment with targeted therapy.- How to generate pathology findings.- AJCC staging.- Conclusion and Remarks.