The Handbook of Medicinal Chemistry
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The Handbook of Medicinal Chemistry

Principles and Practice
 Web PDF
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ISBN-13:
9781782621836
Einband:
Web PDF
Seiten:
753
Autor:
Andrew Davis
eBook Typ:
PDF
eBook Format:
Web PDF
Kopierschutz:
Adobe DRM [Hard-DRM]
Sprache:
Englisch
Beschreibung:

Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry has been revised and brought up to date to cover the past, present and future of the entire drug development process.

Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery.

Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development.

Introduction; Library design; Physicochemical properties and drug design; Computational chemistry; Structure-based drug design; Fragment based design; QSAR; Drug metabolism; Pharmacokinetics; Molecular biology; Computational biology; In vitro; In vivo; Translational science; Assays; Toxicology; Intellectual property; Modern drug design; Lead generation; Lead optimisation; Predictive toxicology; Pharmaceutical development; Process research; Project management; Clinical development; Case Study 1; Case Study 2; Case Study 3