Energy Metabolism and Obesity: Research and Clinical Applications is a compilation of highly informative reviews written by undisputed leaders in the field. These authors elucidate the most important aspects of genetic background, neuropeptide secretion and action, neuronal pathways, adipokines, gut hormones, and environmental influences (physical activity, pharmacologic agents, and surgical alteration of the gastrointestinal tract), as well as the complex interactions among them. Understanding the physiology of energy storage and partitioning has become quite a daunting task. This title enables researchers and clinicians to face the challenge of understanding this complex topic and applying the information to the practice of obesity prevention and treatment. The excellent overviews in this book will undoubtedly provide readers with a better understanding of the multifaceted entity of obesity.
This unique and authoritative book presents an up-to-date overview of the many aspects of energy balance and its relationships to disease processes resulting from excess energy consumption and storage. It provides a comprehensive treatment of important research and clinical aspects of energy metabolism and obesity. It will be a valuable resource for endocrinologists, diabetes specialists, internists and family practitioners.
Table of Contents Contemporary Endocrinology Energy Metabolism and Obesity: Research and Clinical Applications Editor: Patricia A. Donohoue, MD Professor of Pediatrics, Division of Endocrinology and Diabetes University of Iowa Carver College of Medicine Children’s Hospital of Iowa at University of Iowa Hospitals and Clinics 200 Hawkins Drive, 2858 JPP Iowa City, IA 52242-1083 Phone 319-356-3164 FAX 319-356-8170 Chapter 1: Molecular Physiology of Monogenic and Syndromic Obesities in Humans Wendy K. Chung and Rudolph L. Leibel Chapter 2 : Leptin Signaling In the Brain Ofer Reizes, Stephen C. Benoit, and Deborah J. Clegg Chapter 3: Inactivating Melanocortin-4 Receptor Mutations and Human Obesity Ya-Xiong Tao Chapter 4: The Role of Central Melanocortins in Cachexia Daniel L. Marks Chapter 5: The Efferent Arm of the Energy Balance Regulatory Pathway: Neuroendocrinology and Pathology Robert H. Lustig Chapter 6: Adiponectin: A Multifunctional Adipokine Kristen Clarke and Robert L. Judd Chapter 7: The Role of the Gastrointestinal Hormones Ghrelin, Peptide YY and Glucagon-like Peptide-1 in the Regulation of Energy Balance Ruben Nogueiras, Hilary Wilson, Diego Perez-Tilve and Matthias H. Tschöp Chapter 8: The Role of GHSs/Ghrelin in Feeding and Body Composition Cyril Y. Bowers, Blandine Laferrere, David Hurley, and Johannes D. Veldhuis Chapter 9: Interaction Between Physical Activity and Genetic Factors in Complex Metabolic Disease Paul W. Franks and Stephen M. Roth Chapter 10: 11ß-Hydroxysteroid Dehydrogenase Type 1 and Obesity Roland H. Stimson and Brian R. Walker Chapter 11:Prader-Willi Syndrome (PWS): A Model of Disordered Energy Homeostasis Andrea Haqq Chapter 12: Antipsychotic Medication-Induced Weight Gain and Risk for Diabetes and Cardiovascular Disease John W. Newcomer Chapter 13: Treatment of Insulin Resistance in Youth: The Role of Metformin Molly Emott and Michael Freemark Chapter 14: The Surgical Approach to Morbid Obesity Edward E. Mason, Mohammad K. Jamal and Thomas O’Dorisio