Atlas of Hypertension

'In this edition of the Atlas of Hypertension, Dr. Norman Hollenberg and more than 20 leading authorities have worked together to capture the most updated and pertinent information in the field of hypertension. This new edition is a modern and complete visual library of up-to-date information on the most current pharmacologic and treatment advances in the field. With over 600 vivid illustrations, clinical photographs, instructive diagrams and charts, this updated reference provides a detailed and accurate insight into treatment and management of hypertension, covering a full range of topics. Together with detailed legends and extensive reference listings, the illustrations deliver comprehensive guidance to effective diagnosis and treatment of a wide breadth of these clinical challenges.

1 Pathogenesis of Hypertension: Genetic and Environmental Factors.- Genetic Factors in Hypertension.- Environmental Factors in Hypertension.- Gene-Environment Interactions in Hypertension.- 2 Role of the Nervous System in Human Hypertension.- Functional Organization of the Autonomic Nervous System.- Factors Affecting the Autonomic Control of Blood Pressure in Humans.- Testing Autonomic Function in Humans.- The Autonomic Nervous System in Human Hypertension.- Obesity, Hypertension, and the Sympathetic Nervous System.- 3 Kidney, Sodium, and the Renin-Angiotensin System.- Anatomy and Physiology.- Pathophysiology.- Renovascular Hypertension.- 4 Pathogenesis of Hypertension: Vascular Mechanisms.- Identification of the Problem.- Morphologic Changes in Hypertension.- Mechanisms Underlying Structural Changes.- Functional Alterations in Hypertension.- 5 Cardiovascular Risk Assessment in Hypertension.- 6 Secondary Hypertension: Adrenal and Nervous Systems.- Adrenocortical Causes of Hypertension.- Hypertensive Syndromes Secondary to Hypersecretion of Deoxycorticosterone.- Hypertensive Syndromes Secondary to Cortisol Excess.- Hypertensive Syndromes Secondary to Hypersecretion of Aldosterone.- Pheochromocytoma.- 7 Antihypertensive Agents: Mechanisms of Drug Action.- Individualized Antihypertensive Therapy.- Diuretics.- ß-Blockers.- Angiotensin-Converting Enzyme Inhibitors.- Calcium Antagonists.- Other Agents.- Angiotensin II Antagonists.- Metabolic Effects of Antihypertensive Drugs.- Regression of Vascular and Cardiac Hypertrophy.- 8 Recent Therapeutic Trials.- Target Organ Protection.- Trends in Cardiovascular Disease.- Early Trials.- Meta-analysis of Pre-1990 Trials.- Recent Trials (Reported After the JNC-VI Report).- 9 Antihypertensive Therapy: Patient Selection and SpecialProblems.- Hypertension and Cardiovascular Risk.- Nonpharmacologic Therapy.- Factors in the Selection of Antihypertensives.- Concomitant Disease and Quality of Life.- 10 Antihypertensive Therapy: Progression of Renal Injury.- Overview.- Epidemiology.- Neurohormonal Responses.- Clinical Considerations.- Experimental Trials with ACE Inhibitors.- Human Clinical Trials.- Effects of Antihypertensive Drugs on Nondiabetic Renal Disease.- Effects of Drugs on Diabetic Renal Response.- 11 Antihypertensive Therapy: Compliance and Quality of Life.- Background.- Assessment Techniques.- Application to Antihypertensive Therapy.- Clinical Relevance and Sensitivity.- Future Directions.- 12 Special Situations in the Management of Hypertension.- Hypertension in Pregnancy.- Hypertension at the Extremes of Age.- Hypertension at the Extremes of Severity.- Hypertension-causing Drugs.- Specialized Methods of Blood Pressure Measurement.- 13 Recommendations of the Ada and Summary of the JNC and WHO-ISH Special Reports.- Joint National Committee-V.- World Health Organization-International Society of Hypertension.- 14 Newer Antihypertensive Agents.- Angiotensin-receptor Antagonists.- Receptor Binding and Pharmacologic Effects.- Selective Aspects of Pharmacology.- Recent Clinical Trials of Angiotensin-receptor Antagonists.- Vasopeptidase Inhibitors.- 15 Accurate and Reliable Blood Pressure Measurement in the Clinic and Home.- History and Significance of Proper Blood Pressure Measurement.- Technique and Equipment.- Cuff Placement and Pulse Detection.- Recording the Pressure and the Auscultatory Gap.- Quality Assurance.