Aging and Heart Failure

Ch. 1: Changing demographics of the aging population with heart failure and implications for therapy

Bodh I. Jugdutt

Ch. 2: Biology of aging and implications for heart failure therapy and prevention

Bodh I. Jugdutt

Ch. 3: Hypertension and prevention of diastolic heart failure in the aging population

Wilbert S. Aronow

Maciej Banach

Ali Ahmed

Ch. 4: Aging and optimal therapy of systolic heart failure in the elderly

Nakul Chander Sharma

Bodh I. Jugdutt

Ch. 5: Atrial fibrillation and heart failure in the aging population

Pedram Kazemian

Bodh I. Jugdutt

Ch. 6: Optimizing therapy of heart failure in the aging population with monitoring in clinics

John R. Dimitry

Justin A. Ezekowitz

Ch. 7: Cardiac alterations in aging, hypertension and diastolic heart failure

Edith Pituskin

D. Ian Paterson

Ch. 8: Polypharmacy and adverse drug reactions in the aging population with heart failure

Michael W. Rich

William J. Nienaber

Ch. 9: Aging-related changes in vascular biology and implications for heart failure therapy in the aging population

Michael Sean McMurtry

Ch. 10: Biomarkers and optimal management of heart failure in the aging population

Hanna K. Gaggin

James L. Januzzi, Jr.

Ch. 11: Benefits of Exercise in the elderly

Ezra A. Amsterdam

C. Tissa Kappagoda

Ch. 12: The RAAS in heart failure: an update on clinical trials and opportunities for therapy

C. Tissa Kappagoda

Ezra A. Amsterdam

Ch. 13: Aging and diastolic dysfunction - the interplay of inflammation and extracellular matrix regulation

Peter Moritz Becher

Dirk Westermann,

Carsten Tschöpe

Ch. 14: Reperfusion and vasodilator therapy in elderly patients with STEMI and heart failure. Improving outcomes

Bodh I. Jugdutt,

Anwar Jelani

Seraj Abualnaja

Nakul Chander Sharma

Joseph Szeman Wong

Ch. 15: Erythropoietin therapy for heart failure

Margarita Borovka

Mathew S. Maurer

Ch. 16: Role of resistin in heart failure in the elderly

Yasuchika Takeishi

Ch. 17: Role of coronary artery calcium in cardiovascular risk stratification and management in the aging population

Craig R. Butler

Paolo Raggi

Ch. 18: Aging-and remodeling of the RAS and RAAS and related pathways. Implications for heart failure therapy

Bodh I. Jugdutt

Ch. 19: Aging and right ventricular failure from pulmonary hypertension: Effect of right ventricular and pulmonary artery remodeling

Joseph Szeman Wong

Bodh I. Jugdutt

Ch. 20: Biomarkers of cardiovascular aging

Nirankar S. Neki

Paramjit S. Tappia

Naranjan S. Dhalla

Ch. 21: Changes in the heart that accompany advancing age: Humans to molecules

Edward G. Lakatta

Harold A. Spurgeon

Andzej M. Janczewski

Ch. 22: Aging-related changes in cell death and cell survival pathways and implications for heart failure therapy

Guido R.Y. De Meyer

Dorien M. Schrijvers

Wim Martinet

Ch. 23: Aging-related changes in telomeres and telomerases and implications for heart failure therapy

Pim van der Harst

Dirk J. van Veldhuisen

Ch. 24: Aging associated alterations in myocardial inflammation and fibrosis: pathophysiological perspectives and clinical implications

Arti V. Shinde

Nikolaos G Frangogiannis

Ch. 25: Aging-related changes in extracellular matrix: implications for ventricular remodeling following myocardial infarction

Nguyen T. Nguyen

Andriy Yabluchanskiy

Lisandra E. de Castro Brás

Yu-Fang Jin

Merry L. Lindsey

Ch. 26: Calcium handling defects and changes in cardiac function in the aging heart

Adriana Adameova

Nirankar S. Neki

Paramjit S. Tappia

Naranjan S. Dhalla

Ch. 27: Integrins: Implications for aging in heart failure therapy

Laura L. Daniel

William L. Joyner

Mahipal Singh

Krishna Singh

Ch. 28: Adipokines as novel biomarkers in aging and heart failure

Ken Shinmura

Ch. 29: Aging-related changes in cellular and molecular mechanisms of post-infarction remodeling. Implications for heart failure therapy

Henry Han-Jen Shih

Andrew J. Boyle

Ch. 30: Aging-related changes in mitochondrial function and implication for heart failure therapy

Satoaki Matoba

Atsushi Hoshino

Hiroaki Matsubara

Ch. 31: Regulation of SERCA via oxidative modifications: Implications for the pathophysiology of diastolic dysfunction in the aging heart

Fuzhong Qin

Richard A. Cohen

Wilson S. Colucci

Ch. 32: SMP-30 and aging-related cardiac remodeling and heart failure

Satoshi Suzuki