Oxygen Transport to Tissue IX

These papers stem from the ISOTT Meeting held at Churchill College, Cambridge, from July 27th to 30th, 1986. Although the sun did not shine so brightly as during the Cambridge meeting in 1977, the communications and discussions were as lively and informative and some heat, as well as light, was generated in the presentation of differing views. The meeting was conducted in a generally informal way which allowed maximum time for discussion but the relatively unstructured nature of the debates made them unsuitable for publication. The amount of editing necessary meant that the printed version of the exchanges would bear little resemblance to the original, hence their omission. All the papers presented here have been scrutinized and retyped in a standard format. However, the diverse interests of ISOTT's members, reflected in the wide spectrum of the material submitted, made total editorial uniformity an unrealistic goal. Complete consistency in the use of symbols, abbreviations and units seemed less important than speed of publication.

Springer Book Archives

Methods.- Morphometric Analysis of Sparse Capillary Networks.- A Comparison of the Methods for Assessment of the Heterogeneity in Myocardial Capillary Spacing.- Imaging of Red Blood Cell and Plasma Dispersion in the Brain Cortex.- Determination of Cerebral Cortical Capillary Blood Volume from Mean Transit Time Analysis.- The Microphotometric Determination of the Variability of the O2 Saturation of Erythrocytes Lying within Rouleaux.- Kinetics and Transient Times of Fluorescence Optical Sensors (Optodes) for Blood Gas Analysis (O2, CO2, pH).- A Method for Estimating Contact Time of Red Cells in Lung Capillaries from O2 and CO2 Concentrations in Rebreathing Air in Man.- Quantitative Relations between Gas Exchange Parameters including Contact Time at Rest and during Treadmill Exercise.- A Versatile and Sensitive Method for Measuring Oxygen.- Blood Substitutes.- Critical Oxygen Delivery Levels during Shock following Normoxic and Hyperoxic Haemodilution with Fluorocarbons or Dextran.- Prophylaxis and Treatment of Myocardial Ischaemia by Haemodilution with Fluorocarbon Emulsions.- Emulsified Perfluorochemicals as Physiological Oxygen-transport Fluids: Assessment of a Novel Formulation.- Cerebral Cortical Oxygenation and Perfusion during Progressive Normavolaemic Haemodilution with Hetastarch (Volex) and Fluosol-DA.- Oxygen Transport to Renal Tissue: Effect of Oxygen Carriers.- Highly Polymerized Human Haemoglobin as an Oxygen-carrying Blood Substitute.- Modelling.- Oxygen Boundary Crossing Probabilities.- In vivo Recruitment of Mitochondrial VO2: Test of Current Models using Tissue Data.- A Comparison of a Four Wavelength Analysis and Multicomponent Wave-length Analysis Applied to Determination of Haemoglobin Saturation.- Time Courses of Erythrocytic Oxygenation in Capillaries of the Lung: Lower and Upper Bounds on Red Cell Transit Times.- Diffusion Pathways in Oxygen Supply of Cardiac Muscle.- Simulation of the Point Spread Function for Light in Tissue by a Monte Carlo Technique.- Use of Adair Four-step Kinetics in Mathematical Simulation of Oxygen Transport in the Microcirculation.- Physiology.- Arterial Obstruction Induced by PAF-acether (1-0-alkyl-SNglycero-3-phosphocholine).- Anti-anaphylactic Properties of BN 52021: A Potent Platelet Activating Factor Antagonist.- Role of hypoxia and acetylcholine in the regulation of cerebral blood flow.- Adaptation to Hypoxia.- Changes in the Endoplasmic Reticulum following Exposure to Hypoxia.- Cerebral Microcirculatory Changes during Exposure to Hypoxia.- Metabolic, Ionic and Electrical Activities during and after Incomplete or Complete Cerebral Isthaemia in the Mongolian Gerbil.- Inside a Quantitative Analysis of In Vivo near Infrared Monitoring.- Near-infrared Spectrophotometric Monitoring of Haemoglobin and Cyto-chrome a,a3In Situ.- Simultaneous Measurement of Haemoglobin Oxygenation of Brain and Skeletal Muscle of Rat In Vivo by Near-infrared Spectrophotometry.- Spectroscopic Characteristics of Rat Skeletal and Cardiac Tissues in the Visible and Near-infrared Region.- Non-invasive Near-infrared Measurements of Human Arm Tissues In Vivo.- The Effect of Intracellular Oxygen Concentration on Ventricular Fibrillation in Perfused Rat Heart.- Comparison of Intracellular PO2 and Conditions for Blood-Tissue O2 Transport in Heart and Working Red Skeletal Muscle.- Dynamic Structure of Phospholipid Bilayers on the Path for Oxygen Diffusion in the Ox Lung.- Effects of Temperature on Oxygen Transfer Conductance of Human Red Blood Cells.- Oxygen Tension and Sperm Migration in the Female Bed Bug.- Oxygen Toxicity.- Surfactant in Pulmonary Oxygen Toxicity.- Acute Respiratory Failure Induced by Tracheal Instillation of Xanthine Oxidase, its Prevention and Therapy by Exogenous Surfactant Instillation.- Endotoxin Protection against Pulmonary Oxygen Toxicity and Plasma Prostaglandin Levels in the Rat.- Survival Time of Rats Exposed to Different High Oxygen Pressures after Administration of Perfluorochemicals.- Effect of Antioxidants on the Biochemical Response in the Oxygen-exposed Rat.- Tumours.- Tumour Blood Flow following Local Ultrasound Heating Computed from Thermal Clearance Curves.- Oxygen Consuming Regions in EMT60/Ro Multicellular Tumour Spheroids Determined by Nonlinear Regression Analysis of Experimental PO2 Profiles.- Oxygen Consumption Rate of Tumour Cells as a Function of their Proliferative Status.- Blood Flow, Vascular Resistance and Oxygen Availability in Malignant Tumours upon Intravenous Flunarizine.- Author index.