Neuroendocrine Molecular Biology

The 13th Annual Meeting of the Foundation was held in Edinburgh during September 1985. The subject was neuroendocrine molecular biology which brought together leading scientists in the fields of molecular genetics, neuroendocrinology and developmental neuro biology. The conference was most stimulating and as the Proceedings show, novel data presented was of the highest quality. The topics presented were grouped under the headings;, "Molecular Biology of the Nervous System", ''IlIRH - New Perspectives', ''Neuropeptides'', "Oxytocin and Vasopressin", "Transcriptional and Post-Translational Regulation of Neuropeptide Synthesis", "Neuroendocrine Mechanisms at the Cellular Level", "Receptors - Cellular and Molecular Biology" and "Clinical Applications". The

Springer Book Archives

Molecular Biology of the Nervous System.- Structure, Function and Expression of the Human Calcitonin /?-CGRP Gene.- Neuronal Specific Gene Expression in the Murine Hippocampus.- Hybridization Histochemistry - Locating Gene Expression.- The Identification and Function of Differentiation Antigens on Primary Sensory Neurons.- LHRH - New Perspectives.- The Physiological Actions of LHRH: Evidence from the Hypogonadal (hpg) Mouse.- The Biosynthetic Precursor of Gonadotropin - Releasing Hormone: A Multifunctional Prohormone.- Gonadotropin-Releasing Hormone: Differentiation of Structure and Function During Evolution.- The Biosynthesis of LHRH.- Evidence for Sex Differences in GnRH Receptors and Mechanism of Action.- The Role of Brain Peptides in the Control of Anterior Pituitary Hormone Secretion.- Phospholipid Turnover, Ca2+ Mobilization and Protein Kinase C Activation in GnRH Action on Pituitary Gonadotrophs.- Hormonal Regulation of Pituitary Gonadotropin Gene Expression.- Neuropeptides.- The Mammalian Tachykinins and Their Receptors: Structure-Activity Relationship of the Manmalian Tachykinins.- Biosynthesis of the Tachykinins and Somatostatin.- Biosynthesis of Somatostatin, Vasoactive Intestinal Polypeptide, and Thyrotropin Releasing Hormone.- Enzymes Processing Somatostatin - Precursors, The Somatostatin-28 Convertase of Rat Brain, A System Converting Somatostatin-28 to Both Somatostatins-14 and -28 (1-12).- Oxytocin and Vasopressin.- Oxytocin and Vasopressin Secretion: New Perspectives.- Organization and Expression of the Vasopressin and Oxytocin Genes.- Measurement of Expression of the Vasopressin and Oxytocin Genes in Single Neurons by In Situ Hybridization.- Neurohypophysial Peptides in the Gonads.- Molecular Biology of Ovarian Oxytocin.- Characterization,Regulation and Functional Activity of Specific Vasopressin Receptors in the Anterior Pituitary Gland.- Transcriptional and Post-Translational Regulation of Neuropeptide Synthesis.- The Regulation of Proopiomelanocortin Gene Expression by Estrogen in the Rat Hypothalamus.- Differential Regulation of ACTH and ?-Endorphin by Controlled Processing.- Strategies in the Regulation of Secretory Signals from Proopiomelanocortin-Producing Cells.- Expression of Preprosomatostatin Genes in Heterologous Cells.- Degradation of Luteinizing Hormone-Releasing Hormone (LHRH) by Pituitary Plasma Membrane and by Pituitary Cells in Culture.- Neuroendocrine Mechanisms at the Cellular Level.- Analysis of Hormone Secretion from Individual Pituitary Cells.- LHRH Priming in Gonadotrophs: A Model System for the Analysis of Neuroendocrine Mechanisms at the Cellular Level.- Membrane Traffic in Relation with Release Mechanisms in Neuroendocrine Cells in Culture.- Neuro-Steroids: 3?-Hydroxy-?5-Derivatives in the Rat Brain.- Ion Channels and the Control of Secretion in Normal Anterior Pituitary Cells.- Receptors - Cellular and Molecular Biology.- Biochemical and Functional Characterization of GnRH Receptors.- Hormonal Receptor Plasticity in the Brain as Shown by In Vitro Quantitative Autoradiography.- Cytosolic Factors Modulating Prolactin Binding.- Pituitary GnRH Receptors - Recent Studies and Their Functional Significance.- Effects of an LHRH Antagonist on Luteal Function in the Macaque.- Clinical Applications.- Comparison of Protein and Ribonucleic Acid Composition of Post Mortem Brain Tissue Between Controls and Cases of Alzheimer Type Dementia.- Neuroendocrine Changes in Alzheimer's Disease: Raised Plasma Concentrations of Growth Hormone and Thyroid Stimulating Hormone and ReducedConcentrations of Oestrogen-Stimulated Neurophysin.- The Use of an LHRH Agonist in the Treatment and Investigation of the Premenstrual Syndrome.- Direct Effects of LHRH and Agonists on Human Breast Cancer Cells.