Central Nervous System Intraoperative Cytopathology

César R. Lacruz, MD, PhD, FIAC Consultant Pathologist, Assistant Professor PathologyUniversity General Hospital "Gregorio Marañón", Department of Pathology, Madrid, SpainJavier Saénz de Santamaría, MD, PhD, FIAC Director of Anatomic Pathology, Professor of Pathology University Hospital, Extremadura Medical School, Badajoz, SpainRicardo H. Bardales, MD, MIAC Staff PathologistOutpatient Pathology Associates, Sacramento, CA, USA

The Essentials in Cytopathology book series fulfills the need for an easy-to-use and authoritative synopsis of site specific topics in cytopathology. These guide books fit into the lab coat pocket and are ideal for portability and quick reference. Each volume is heavily illustrated with a full color art program, while the text follows a user-friendly outline format.

Central Nervous System Intraoperative Cytopathology covers the full spectrum of benign and malignant conditions of the CNS with emphasis on common disorders. The volume is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in the field of intraoperative neuro-cytopathology. Central Nervous System Intraoperative Cytopathology is a valuable quick reference for pathologists, cytopathologists, and fellows and trainees dealing with this exigent field.

This book covers the full spectrum of benign and malignant conditions of the central nervous system with an emphasis on common disorders. It contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities.

Chapter 1 Introduction to CNS Intraoperative Cytopathology
Historical Background
Accuracy of CNS Intraoperative Cytopathology
Histologic Types of CNS Neoplasms

Chapter 2 Clinical, Radiologic, and Technical Considerations
Clinical Considerations
Radiologic Considerations
Technical Considerations

Chapter 3 Algorithmic Approach to CNS Intraoperative Cytopathology
Sample Triage
Smear Evaluation
General Category Interpretation

Chapter 4 Normal Brain and Gliosis
White Matter Pattern
Gray Matter Pattern
Cerebellar Cortex Pattern
Choroid Plexus Pattern
Leptomeningeal Pattern
Reactive gliosis
Contaminants

Chapter 5 Astrocytic Tumors
Diffusely Infiltrating Astrocytomas
Diffuse Astrocytoma
Anaplastic Astrocytoma
Glioblastoma
Pilocytic astrocytoma
Special Astrocytic Tumors
Subependymal Giant Cell Astrocytoma
Pleomorphic Xanthoastrocytoma
Gliomatosis Cerebri

Chapter 6 Oligodendroglial Tumors
Oligodendroglioma
Anaplastic Oligodendroglioma

Chapter 7 Ependymal Tumors
Ependymoma
Anaplastic Ependymoma
Subependymoma
Myxopapillary Ependymoma

Chapter 8 Choroid Plexus Tumors
Choroid Plexus Papilloma
Choroid Plexus Carcinoma

Chapter 9 Neuronal and Glioneural Tumors
Desmoplastic Infantile Ganglioglioma/Astrocytoma
Dysembryoplastic Neuroepithelial Tumor
Gangliocytoma and Ganglioglioma
Central Neurocytoma
Spinal Paraganglioma

Chapter 10 Embryonal Tumors
Medulloblastoma
Primitive Neuroectodermal Tumors
Atypical Teratoid-Rhabdoid Tumor

Chapter 11 Meningeal Tumors
Meningioma
Hemangioblastoma
Hemangiopericytoma

Chapter 12 CNS Germ Cell Tumors
Germinoma
Teratomas
Malignant Non-germinomatous Germ Cell Tumors

Chapter 13 Tumors of the Hematopoietic System
Primary CNS Lymphoma
Plasmacytoma
Granulocytic Sarcoma
Histiocytic Lesions

Chapter 14 Tumors of the Cranial and Spinal Nerves
Schwannoma
Neurofibroma

Chapter 15 Tumors of the Pineal Region
Pineocytoma
Pineoblastoma
Pineal Glial Cyst

Chapter 16 Tumors of the Sellar Region
Pituitary Adenoma
Craniopharyngioma
Other Lesions of the Sellar Region

Chapter 17 Metastatic Tumors

Chapter 18 Benign Cystic Lesions
Squamous Epithelium-Lined Cysts
Columnar Epithelium-Lined Cysts
Non Epithelial-Lined Cysts

Chapter 19 Non-Neoplastic Disorders
Acute Inflammatory Cell-Rich Lesions
Epithelioid-Cell and Lymphoid-Cell Rich Lesions
Macrophage-Rich Lesions
Inflammatory Lesions in AIDS
Chapter 20 Extradural Mass Lesions Compressing the Spinal Cord
Neoplastic Lesions
Non Neoplastic Lesions