Bone Metastases

This book will be an introduction to bone metastases for orthopaedic surgeons. It covers the basic principles of surgery in bone cancer; radiographic imaging of skeletal metastases; classification; medical treatment; radiotherapy; surgical treatment, incidence and pain relief.
Steady progress in diagnosis and treatment of bone cancer in the last decade has dramatically changed the prognosis of cancer patients, significantly improving their overall survival rate and quality of life.
Some haematologic malignancies that involve bone may be cured with systemic chemotherapy or radiotherapy, but for most patients with bone metastases, pain relief is the goal of therapy.
Bone Metastases - Medical, Surgical and Radiological Treatment is written by a multidisciplinary team of experts to provide comprehensive coverage of metastatic bone disease.
Dominique G. Poitout is Professor of Surgery and Head of Orthopaedic Department at North Hospital, Marseille, France

This title is an introductory text to bone metastases for orthopaedic surgeons. . It covers the basic principles of surgery in bone cancer; classification; medical treatment; radiotherapy; surgical treatment, incidence and pain relief. Bone metastases are a common cause of morbidity in cancer patients. The debilitating pain that occurs in many patients with advanced malignancies is primarily produced by bone metastases. While almost every malignancy can cause bone metastases, breast cancer, lung cancer, and prostate cancer account for more than 80% of bone metastases. Some hematologic malignancies that involve bone may be cured with systemic chemotherapy or radiotherapy, but for most patients with bone metastases, pain relief is the goal of therapy.

1 Histology and Experimental Study.- 1 Pathology of Bone Metastatic Tumours.- 2 Identification.- 2 Radiographic Imaging of Skeletal Metastases.- 3 Medical Treatment.- 3 Chemotherapy.- 4 Immunotherapy.- 5 Biphosphonates.- 6 Hormonal Therapy.- 7 Cement-Containing Antimitotics.- 4 Radiotherapy.- 8 Radiotherapy in the Treatment of Bone Metastases.- 9 Radiosurgical Treatment of Bone Metastasis of the Limbs.- 5 Surgical Treatment.- 10 Surgery for Bone Metastasis of the Limbs.- 11 Surgical Treatment of Vertebral Metastases.- 12 Treatment of Secondary Spinal Tumours.- 6 Medico-social Aspects.- 13 Caring for Cancer Patients.- 7 Pain Relief.- 14 Therapeutic Approaches to Bone Cancer Pain.- Conclusion.