Although pancreas transplants have been performed for more than 30 years, the last few years have witnessed significant growth in the options available for pancreas transplantation. Transplantation of the Pancreas, edited by Drs. Gruessner and Sutherland provides a state-of-the-art, definitive reference work on pancreas transplantation for transplant surgeons and physicians as well as for endocrinologists, diabetologists, nephrologists, and neurologists. The editors, from the renowned University of Minnesota Transplant Division and the Diabetes Institute, have assembled a group of renowned experts to provide an all-inclusive overview of pancreas transplantation. The text features insights on the pathophysiology of diabetes mellitus and the limitations of nontransplant treatments, highlights experimental research and clinical history of pancreas transplantation, and compares and contrasts different surgical procedures. The discussions detail the broad spectrum of post-transplant complications and their treatments, which frequently require skills in general, vascular, and laparoscopic surgery; interventional radiology; critical care; and infectious disease. Chapters on pretransplant evaluation, immunosuppression, immunology, pathology, long-term outcome, quality of life, and cost-effectiveness focus on issues unique to pancreas recipients. Evolving areas, such as pretransplant evaluation of pancreas transplant candidates, living donation, and the current status of islet transplantation are discussed. Augmented by more than 280 illustrations, including full color line drawings created exclusively for the text, this book is the standard reference for all transplant professionals as well as for all physicians caring for the transplant patient.
1. Diabetes Mellitus, 2. Modern Concepts of Diabetes Mellitus, 3. Limitations of Nontransplant Treatment Options for Type I Diabetes Mellitus, 4. History of Pancreas Transplantation, 5. Experimental Pancreas Transplantation, 6. The Pancreas and Islet Transplant Population, 7. Pretransplant Evaluation, 8. Surgical Aspects of Pancreas Transplantation, 9. Postoperative Management, 10. Immunosuppression In Pancreas Transplantation, 11. Immunobiology, Diagnosis, and Treatment of Pancreas Graft Rejection, 12. Pancreas Graft Pathology, 13. Immunology in Pancreas Transplantation, 14. Living Donor Transplantation, 15. Endocrine Function and Metabolic Outcomes in Pancreas and Islet Transplantation, 16. Effects of Pancreas Transplantation on Secondary Complications of Diabetes, 17. Quality of Life for Pancreas Transplant Recipients, 18. Long-term Pancreas Graft Function, 19. Economic Issues in Pancreas Transplantation, 20. International Pancreas Transplant Registry, 21. Islet Transplantation, 22. Treatment of Pancreatic Excocrine Disorders by Pancreas and Islet Transplantation.