Surgical Management of Vitiligo

Although vitiligo has traditionally been very difficult to treat, a new breakthrough surgical treatment is expanding options for practitioners and patients. Standard treatments depend on the severity of the condition and the patient's feelings of disfigurement. Cover-up cosmetics work well for some people. Other more sophisticated forms of treatment include gradually developing color back in the depigmented areas (repigmentation) by PUVA or other ultraviolet light treatments, but this is extremely slow and intensive, often requiring several hundred treatments. This new form of treatment, which involves surgically transplanting melanocytes into the white areas, is most successful in patients with stable vitiligo over less than 30% of their body surface area. It complements medical therapies in achieving complete and sustained repigmentation and is rapidly gaining popularity in all major centers. This is the first book available which describes this major advance in detail. Explains the new treatment of surgically transplanting melanocytes into the affected areas of the skin to provide dermatologists and surgeons with the latest state-of-the-art information Written by the international leaders who pioneered this treatment Presents all the latest information on the topic, eliminating the need to search through multiple sources for specific data

Although vitiligo has traditionally been very difficult to treat, anew breakthrough surgical treatment is expanding options forpractitioners and patients.Standard treatments depend on the severity of the condition andthe patient's feelings of disfigurement. Cover-up cosmetics workwell for some people. Other more sophisticated forms of treatmentinclude gradually developing color back in the depigmented areas(repigmentation) by PUVA or other ultraviolet light treatments, butthis is extremely slow and intensive, often requiring severalhundred treatments.This new form of treatment, which involves surgicallytransplanting melanocytes into the white areas, is most successfulin patients with stable vitiligo over less than 30% of their bodysurface area. It complements medical therapies in achievingcomplete and sustained repigmentation and is rapidly gainingpopularity in all major centers.This is the first book available which describes this majoradvance in detail.* * Explains the new treatment of surgically transplantingmelanocytes into the affected areas of the skin to providedermatologists and surgeons with the latest state-of-the-artinformation* * Written by the international leaders who pioneered thistreatment* * Presents all the latest information on the topic, eliminatingthe need to search through multiple sources for specific data

Section 1 Pathogenesis and Medical Treatment.1 Pathogenesis of Vitiligo. (Jean-Paul Ortonne).2 Understanding the Mechanism of Repigmentation in Vitiligo.(Amrinder J. Kanwar and Davinder Parsad).3 Classification of Vitiligo. (Sang Ju Lee, Sung Bin Cho andSeung-Kyung Hann).4 Medical Treatment of Vitiligo. (Thierry Passeron and Jean-PaulOrtonne).Section 2 Overview of Surgical Management.5 History and chronology of development of surgical therapiesfor vitiligo. (Rafael Falabella).6 The Concept of Stability of Vitiligo. (Koushik Lahiri andSubrata Malakar).7 Patient Selection and Preoperative Information in SurgicalTherapies for Vitiligo. (Nanny van Geel and Jean MarieNaeyaert).8 Classification of Surgical Therapies for Vitiligo. (PhilippeBahadoran and Jean-Paul Ortonne).9 Surgical Management of Vitiligo and Other Leukodermas:Evidence-based Practice Guidelines. (Somesh Gupta, Tarun Narang,Mats J. Olsson and Jean-Paul Ortonne).10 Evaluation of Outcome in Surgical Therapies for Vitiligo.(Nanny van Geel and Jean Marie Naeyaert).Section 3 Tissue Grafting.11 Minigrafting for Vitiligo. (Subrata Malakar and KoushikLahiri).12 Suction Blister Epidermal Grafting. (Somesh Gupta and AshimaGoel).13 Thin Split-thickness Skin Grafts for Vitiligo. (NitiKhunger).14 Treatment of Leukoderma by Transplantation of Ultra-thinEpidermal Sheets. (Mats J. Olsson).15 Transplantation of Hair Follicles for Vitiligo. (SubrataMalakar, Gun Yoen Na and Koushik Lahiri).16 Mesh Grafts for Vitiligo. (C.R. Srinivas, Reena Rai and M.Sinha).17 Flip-top Pigment Transplantation. (Brent E. Pennington, JeanL. Bolognia and David J. Leffell).18 Ultrasonic Abrasion and Seed Grafts for Vitiligo. (KatsuhikoTsukamoto, Reiko Kitamura and Osami Takayama).19 Complications and Limitations of Melanocyte Transplantation.(Yvon Gauthier).Section 4 Cellular Grafting.20 Treatment of Leukoderma by Transplantation of Basal CellLayer Suspension. (Mats J. Olsson).21 Setting up a Tissue Culture Laboratory. (Rafal Czajkowski,Tomasz Drewa and Waldemar Placek).22 Treatment of Leukoderma by Transplantation of CulturedAutologous. Melanocytes (Mats J. Olsson).23 Transplantation of in Vitro Cultured Epithelial Grafts forVitiligo and Piebaldism. (Liliana Guerra, Sergio Bondanza andDesanka Raskovic).24 Simplifying the Delivery of Cultured Melanocytes andKeratinocytes for Grafting Patients with Vitiligo. (Sheila MacNeiland Paula Eves).25 Safety Concerns in Transplantation of in Vitro CulturedCellular Grafts. (Liliana Guerra, Elena Dellambra and PatriziaPaterna).Section 5 Special Issues.26 Post-surgery Patient Information. (Mats J. Olsson).27 Surgical Management of Lip Vitiligo. (Somesh Gupta, AshimaGoel and Amrinder J. Kanwar).28 Surgical Management of Vitiligo of Eyelids and Genitals:Special Issues. (Somesh Gupta).29 Surgical Management of Acral vitiligo. (Sharad Mutalik).30 Surgical Management of Leukotrichia. (Karoon Agrawal andAparna Agrawal).31 Surgical Treatments of Leukodermas other than VitiligoVulgaris. (Mats J. Olsson).Section 6 Miscellaneous.32 Micropigmentation. (Gurvinder P. Thami).33 Laser for Repigmenting Vitiligo. (Thierry Passeron andJean-Paul Ortonne).34 Application of Lasers in Transplantation Procedures forVitiligo. (Cengiz Acikel, Ersin Ulkur and Bahattin Celikoz).35 Combining Medical and Surgical Therapies. (Alain Taïeband Yvon Gauthier).36 Surgical Depigmentation of Vitiligo: Bleaching Cream, Laserand Cryosurgery. (Monique R.T.M. Thissen).37 Future directions in Surgical Management of Vitiligo. (YvonGauthier).38 Informed Consent. (Mats J. Olsson)