Biochemistry

Jeremy M. Berg received his B.S. and M.S. degrees in Chemistry from Stanford (where he did research with Keith Hodgson and Lubert Stryer) and his Ph.D. in Chemistry from Harvard with Richard Holm. He then completed a postdoctoral fellowship with Carl Pabo in Biophysics at Johns Hopkins University School of Medicine. John L. Tymoczko is Towsley Professor of Biology at Carleton College, where he has taught since 1976. He currently teaches Biochemistry, the Metabolic Basis of Human Disease, Oncogenes and the Molecular Biology of Cancer, and Exercise Biochemistry and co-teaches an introductory course, Energy Flow in Biological Systems. Gregory J. Gatto, Jr., received his A.B. degree in chemistry from Princeton University, where he worked with Martin F. Semmelhack and was awarded the Everett S. Wallis Prize in Organic Chemistry. Lubert Stryer is Winzer Professor of Cell Biology, Emeritus, in the School of Medicine and Professor of Neurobiology, Emeritus, at Stanford University, where he has been on the faculty since 1976. He received his M.D. from Harvard Medical School.

For four decades, this extraordinary textbook has played a pivotal role in the way biochemistry is taught, offering exceptionally clear writing, innovative graphics, coverage of the latest research techniques and advances, and a signature emphasis on physiological and medical relevance. Those defining features are at the heart of this edition.

This textbook makes the language of the introductory biochemistry course as accessible as possible. Its straightforward and logical organisation enhances clarity by stepping the reader through processes and helping them navigate complex pathways and mechanisms. Biochemistry is available with LaunchPad. LaunchPad combines an interactive ebook with high-quality multimedia content and ready-made assessment options, including LearningCurve adaptive quizzing. See 'Instructor Resources' and 'Student Resources' for further information.

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Part I THE MOLECULAR DESIGN OF LIFE
1. Biochemistry: An Evolving Science
2. Protein Composition and Structure
3. Exploring Proteins and Proteomes
4. DNA, RNA, and the Flow of Genetic Information
5. Exploring Genes and Genomes
6. Exploring Evolution and Bioinformatics
7. Hemoglobin: Portrait of a Protein in Action
8. Enzymes: Basic Concepts and Kinetics
9. Catalytic Strategies
10. Regulatory Strategies
11. Carbohydrates
12. Lipids and Cell Membranes
13. Membrane Channels and Pumps
14. Signal-Transduction Pathways

Part II TRANSDUCING AND STORING ENERGY
15. Metabolism: Basic Concepts and Design
16. Glycolysis and Gluconeogenesis
17. The Citric Acid Cycle
18. Oxidative Phosphorylation
19. The Light Reactions of Photosynthesis
20. The Calvin Cycle and the Pentose Phosphate Pathway
21. Glycogen Metabolism
22. Fatty Acid Metabolism
23. Protein Turnover and Amino Acid Catabolism

Part III SYNTHESIZING THE MOLECULES OF LIFE
24. The Biosynthesis of Amino Acids
25. Nucleotide Biosynthesis
26. The Biosynthesis of Membrane Lipids and Steroids
27. The Integration of Metabolism
28. DNA Replication, Repair, and Recombination
29. RNA Synthesis and Processing
30. Protein Synthesis
31. The Control of Gene Expression in Prokaryotes
32. The Control of Gene Expression in Eukaryotes

Part IV RESPONDING TO ENVIRONMENTAL CHANGES
33. Sensory Systems
34. The Immune System
35. Molecular Motors
36 Drug Development