Metal Toxicology Handbook

Debasis Bagchi, Manashi Bagchi

This book covers toxic metals individually discussing their redox biology and cytotoxicity, toxicological aspects on animals and humans, disease manifestations and threshold, organ specific damage, and molecular toxicology including mechanistic insight. It also discusses appropriate doses for beneficial micronutrients or essential trace elements.

Part I: Introduction: Metals, Metalloids, Redox Biology, and Neurodegeneration 1. Role of Metals and Metalloids in Redox Biology 2. Role of Metals in Neurodegeneration Part II: Pathology of Metal Toxicity 3. Pathological Manifestations and Mechanisms of Metal Toxicity 4. An Overview of Heavy Metal Research in Traditional Chinese Medicine Part III: Mechanisms of Restoring Metabolic Homeostasis 5. Development and Utilization of a Novel Prodosomed-Electrolyte and Phytochemical Formulation Technology to Restore Metabolic Homeostasis 6. Gut Microbiome and Heavy Metals Part IV: Radionuclides Toxicity 7. A Review on Radionuclide Toxicity Part V: Benefits of Metals 8. Contribution of Bioavailable Silicon in Human Health 9. Benefits of Trivalent Chromium in Human Nutrition? 10. Trivalent Chromium: A Vital Insulin Sensitizer 11. Differential Impact of Organic Vanadium Compounds on Human Health: Deficiency States, Toxic Effects, and Potential Therapeutic Use 12. Vanadium-Speciation Chemistry Can Be Important When Assessing Health Effects on Living Systems Part VI: Toxic Manifestations by Diverse Heavy Metals and Metalloids 13. Clinical Toxicology of Copper: Source, Toxidrome, Mechanism of Toxicity and Management 14. Cadmium Exposure and Toxicity 15. Cobalt Toxicity and Human Health 16. Cobalt Toxicity 17. Iron-Siderophore and Tumorigenesis: Molecular Insight and Therapeutic Targets 18. Clinical Toxicology of Iron: Source, Toxidrome, Mechanism of Toxicity, and Management 19. Vanadium Toxicity Revisited: Striking the Right Balance between Potential New Generation Therapeutics and Adverse Side Effects 20. The Ubiquitous Lead-Biological Effects, Toxicity, and Management 21. Lead Toxicity: An Overview of Its Pathophysiology and Intervention Strategies 22. Arsenic Toxicity: Source, Mechanism, Global Health Complication, and Possible Way to Defeat 23. Clinical Toxicology of Mercury: Source, Toxidrome, Mechanism of Toxicity, and Management 24. An Overview of Tungsten Toxicity 25. Boron Toxicity: An Insight on Its Influence on Wheat Growth 26. Diversity of Mechanisms for Boron Toxicity in Mammals 27. Lithium: Is It Good or Bad for Plant Growth? 28. An Overview of Nickel Toxicity in Plants Commentary: A Treatise on Metal Toxicology