Microneedle-mediated Transdermal and Intradermal Drug Delivery

Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vaccines and medicines that are unsuitable for oral administration or conventional patch delivery. Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transdermal and intradermal delivery research using microneedles and includes the outcomes of in vivo animal and human studies. Importantly, it also discusses the safety and patient acceptability studies carried out to date. Finally, the book reviews the recent patents in microneedle research and describes the ongoing developments within industry that will determine the future of microneedle-mediated transdermal and intradermal drug delivery. By an expert author team with practical experience in the design and development of drug delivery systems this is the only text that provides a comprehensive review of microneedle research in transdermal and intradermal drug delivery.

Microneedles can be used for delivery of a wide range of drugsubstances for practically any medical condition and present a realopportunity for vaccines and medicines that are unsuitable for oraladministration or conventional patch delivery.Microneedle-mediated Transdermal and Intradermal DrugDelivery covers the major aspects relating to the use ofmicroneedle arrays in enhancing drug delivery applications. Itprovides an overview of the various methods employed to design andproduce microneedles, from the different materials involved to theimportance of application methods. It carefully and criticallyreviews ongoing transdermal and intradermal delivery research usingmicroneedles and includes the outcomes of in vivo animal and humanstudies. Importantly, it also discusses the safety and patientacceptability studies carried out to date. Finally, the bookreviews the recent patents in microneedle research and describesthe ongoing developments within industry that will determine thefuture of microneedle-mediated transdermal and intradermal drugdelivery.By an expert author team with practical experience in the designand development of drug delivery systems this is the only text thatprovides a comprehensive review of microneedle research intransdermal and intradermal drug delivery.

Preface.About the Authors.1 Transdermal Drug Delivery.2 Microneedles: Design, Microfabrication and Optimization.3 Microneedle Applicator Designs for Transdermal Drug Delivery Applications.4 Transdermal Delivery Applications.5 Microneedle-mediated Intradermal Delivery.6 Clinical Application and Safety Studies of Microneedles.7 Microneedles: Current Status and Future Perspectives.Index.