Equine Laminitis

James K. Belknap, DVM, PhD, Diplomate ACVS, is Professor of Equine Surgery in the Department of Veterinary Clinical Sciences at Ohio State University in Columbus, Ohio, USA. He runs a research laboratory studying the pathophysiology of equine laminitis, and works closely with the Certified Journeyman Farrier, Todd Adams, on podiatry cases including equine laminitis cases.

The first book dedicated to this common, serious, and complex equine disease, Equine Laminitis is the gold-standard reference to the latest information on every aspect of the disease and its treatment.
* Provides the first book devoted specifically to equine laminitis
* Discusses the current state of knowledge on all aspects of the disease, including its history, relevant anatomical considerations, pathophysiology, the diagnostic workup, and clinical treatment
* Presents 50 chapters written by leading international experts, under the editorship of the foremost authority on equine laminitis
* Offers a thorough understanding of this common affliction, grounded in the scientific literature
* Describes effective prevention and treatment plans

Contributors, vii
 
Foreword, x
 
Abbreviations, xii
 
Part 1: Overview: From Basic Research to Caring for the Laminitis Patient
 
1 Historical Perspective on Equine Laminitis, 3
Donald M.Walsh and Teresa A. Burns
 
2 Laminitis: An Overview, 11
James K. Belknap
 
3 Anatomy and Function of the Equine Digit, 13
A.H. Parks
 
4 Lamellar Function at the Cellular Level, 22
Christopher C. Pollitt
 
5 Digital Biomechanics Relevant to Laminitis, 39
Jonathan Merritt, Helen Davies and Andrew H. Parks
 
Part 2: Pathophysiology of Laminitis
 
6 Overview, 51
James K. Belknap
 
7 Experimental Models of Laminitis: Starch Overload, 54
Susan C. Eades
 
8 Experimental Models of Laminitis: Oligofructose Overload, 59
Christopher C. Pollitt and Gabriel J. Milinovich
 
9 Experimental Models of Laminitis: BlackWalnut Extract, 64
John F. Peroni
 
10 Experimental Models of Laminitis: Hyperinsulinemia, 68
Catherine McGowan and Janet Patterson-Kane
 
11 Hemodynamic Events in Laminitis, 75
John F. Peroni, Susan C. Eades and Simon R. Bailey
 
12 The Role of Thrombosis and Coagulation in Equine Laminitis, 82
Simon R. Bailey
 
13 Leukocytes and Inflammatory Signaling in Laminitis: Leukocytes, 91
Rafael R. Faleiros and James K. Belknap
 
14 Leukocytes and Inflammatory Signaling in Laminitis: Inflammatory Signaling, 102
Britta Leise
 
15 Role of Proteases in Laminitis, 115
Samuel J. Black, LeWang, Erica Pawlak, Fengqiu Zhang, John Loftus and Dominique Alfandari
 
16 Endocrine and Metabolic Dysregulation in Laminitis: Role of Pituitary Dysfunction, 134
Philip J. Johnson
 
17 Endocrine and Metabolic Dysregulation in Laminitis: Role of Corticosteroids, 141
Philip J. Johnson
 
18 Metabolic Syndrome in Humans and Horses: The Relationship Between Obesity and Insulin Resistance, 149
Teresa A. Burns and Ramiro E. Toribio
 
19 Dysregulation of the Lamellar Basal Epithelial Cell in Laminitis: Role of the Cytoskeleton and Cell Junctions, 167
Christopher C. Pollitt
 
20 Structural Dynamics of Displacement of the Distal Phalanx, 176
Andrew H. Parks
 
Part 3: Clinical Presentation of Equine Laminitis
 
21 General Clinical Aspects of the Laminitis Case, 183
Andrew van Eps
 
22 Sepsis-Related Laminitis, 191
Susan C. Eades
 
23 Laminitis in Equine Metabolic Syndrome, 196
Andy E. Durham
 
24 Laminitis in Pituitary Pars Intermedia Dysfunction, 204
Philip J. Johnson
 
25 Supporting Limb Laminitis, 210
Gary M. Baxter
 
Part 4: Diagnostic Evaluation of Equine Laminitis
 
26 Detailed Physical Examination for Laminitis, 217
Richard A. Mansmann and Hans H. Castelijns
 
27 Diagnostic Imaging, 226
Andrew H. Parks and James K. Belknap
 
28 The Digital Venogram, 240
Amy Rucker
 
29 Endocrine and Metabolic Evaluation in Horses with Laminitis, 252
Ramiro E. Toribio and Teresa A. Burns
 
Part 5: Medical Treatment of the Laminitic Patient
 
30 General Supportive Care for the Laminitis Case, 269
Andrea E. Floyd and Debra R. Taylor
 
31 Common Therapies: Anti-Inflammatory Therapy, 277
Thomas J. Divers
 
32 Vasoactive Drug Therapy, 284
Simon R. Bailey and Susan C. Eades
 
33 Analgesia, 291
Bernd Driessen and Laura Zarucco
 
34 Digital Hypothermia, 306
Andrew W. van Eps and Christopher C. Pollitt
 
35 Equine Sepsis, 316
Samuel D. Hurcombe and Susan J. Holcombe
 
36 Equine Metabolic Syndrome, 329
Andy E. Durham
 
37 Pituitary Pars Intermedia Dysfunction, 334
Dianne McFarlane, Philip J. Johnson and Harold C. Schott

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