Nanobiotechnology in Diagnosis, Drug Delivery and Treatment

Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

Presents nanobiotechnology in drug delivery and disease managementFeaturing contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine.Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more.* Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders* Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials* Introduces nano-based sensors which detect various pathogens* Covers the use of nanodevices in diagnostics and theranosticsNanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

List of Contributors viiPreface xi1 Nanotechnology: A New Era in the Revolution of Drug Delivery, Diagnosis, and Treatment of Diseases 1Avinash P. Ingle, Patrycja Golinska, Alka Yadav, Mehdi Razzaghi-Abyaneh, Mrunali Patel, Rashmin Patel, Yulia Plekhanova, Anatoly Reshetilov, and Mahendra Rai2 Selenium Nanocomposites in Diagnosis, Drug Delivery, and Treatment 25Irina A. Shurygina and Michael G. Shurygin3 Emerging Applications of Nanomaterials in the Diagnosis and Treatment of Gastrointestinal Disorders 47Patrycja Golinska and Magdalena Wypij4 Nanotheranostics: Novel Materials for Targeted Therapy and Diagnosis 63Sougata Ghosh and Rohini Kitture5 Aptamer-Incorporated Nanoparticle Systems for Drug Delivery 95Fahimeh Charbgoo, Seyed Mohammad Taghdisi, Rezvan Yazdian-Robati, Khalil Abnous, Mohammad Ramezani, and Mona Alibolandi6 Application of Nanotechnology in Transdermal Drug Delivery 113Dilesh Jagdish Singhavi and Shagufta Khan7 Superparamagnetic Iron Oxide Nanoparticle-Based Drug Delivery in Cancer Therapeutics 129Dipak Maity, Atul Sudame, and Ganeshlenin Kandasamy8 Virus-Like Nanoparticle-Mediated Delivery of Cancer Therapeutics 153Yasser Shahzad, Abid Mehmood Yousaf, Talib Hussain, and Syed A.A. Rizvi9 Magnetic Nanoparticles: An Emergent Platform for Future Cancer Theranostics 171Parinaz Nezhad-Mokhtari, Fatemeh Salahpour-Anarjan, Armin Rezanezhad, and Abolfazl Akbarzadeh10 Chitosan Nanoparticles: A Novel Antimicrobial Agent 197Divya Koilparambil, Sherin Varghese, and Jisha Manakulam Shaikmoideen11 Sulfur Nanoparticles: Biosynthesis, Antibacterial Applications, and Their Mechanism of Action 217Priti Paralikar and Mahendra Rai12 Role of Nanotechnology in the Management of Indoor Fungi 229Erasmo Gámez-Espinosa, Leyanet Barberia-Roque, and Natalia Bellotti13 Nanotechnology for Antifungal Therapy 259Jacqueline Teixeira da Silva and Andre Correa Amaral14 Chitosan Conjugate of Biogenic Silver Nanoparticles: A Promising Drug Formulation with Antimicrobial and Anticancer Activities 273Smitha Vijayan and Jisha Manakulam Shaikmoideen15 Leishmaniasis: Where Infection and Nanoparticles Meet 295Mohammad Imani and Azam Dehghan16 Theranostics and Vaccines: Current Status and Future Expectations 359Thais Francine Ribeiro Alves, Fernando Batain, Cecília Torqueti de Barros, Kessie Marie Moura Crescencio, Venâncio Alves do Amaral, Mariana Silveira de Alcântara Chaud, Décio Luís Portella, and Marco Vinícius Chaud17 Toxicological Concerns of Nanomaterials Used in Biomedical Applications 375Avinash P. Ingle, Indarchand Gupta, and Mahendra RaiIndex 399