TNM Supplement

The Union for International Cancer Control's (UICC) TNM classification system is the most widely used cancer classification and staging system in the world. It is used to describe the anatomical extent of disease and it is essential to patient care, research and cancer control. This fifth edition of the TNM Supplement: A Commentary of Uniform Use offers practitioners a wealth of material intended to complement the system's day-to-day use. The volume features: Updated definitions of terms used in cancer staging. New sections on carcinomas of the thymus, sarcomas of the spine and pelvis and soft tissue sarcomas of the head and neck, and comprehensive updates to the head and neck carcinomas, carcinomas of the lung and neuroendocrine tumours sections. Frequently asked questions from the UICC helpdesk. The Supplement may be treated as a companion text to the recent eighth edition of the TNM Classification of Malignant Tumours (978-1-119-26357-9), supporting the correct and uniform application of the TNM classification system. The TNM Supplement can also be utilised as a standalone book, providing explanations and examples to answer many questions that arise during the daily use of the TNM cancer classification and staging system, particularly in unusual cases.

The Union for International Cancer Control s (UICC) TNM classification system is the most widely used cancer classification and staging system in the world. It is used to describe the anatomical extent of disease and it is essential to patient care, research and cancer control.This fifth edition of the TNM Supplement: A Commentary of Uniform Use offers practitioners a wealth of material intended to complement the system s day-to-day use. The volume features:* Updated definitions of terms used in cancer staging.* New sections on carcinomas of the thymus, sarcomas of the spine and pelvis and soft tissue sarcomas of the head and neck, and comprehensive updates to the head and neck carcinomas, carcinomas of the lung and neuroendocrine tumours sections.* Frequently asked questions from the UICC helpdesk.The Supplement may be treated as a companion text to the recent eighth edition of the TNM Classification of Malignant Tumours (978-1-119-26357-9), supporting the correct and uniform application of the TNM classification system. The TNM Supplement can also be utilised as a standalone book, providing explanations and examples to answer many questions that arise during the daily use of the TNM cancer classification and staging system, particularly in unusual cases.

Preface viiiOrganizations Associated with the TNM System xiiiNational Committees xiiiAcknowledgements xvAbbreviations xviChapter 1 Explanatory Notes - GeneralThe General Rules of the TNM System 1The TNM Clinical and Pathological Classifications 7Residual Tumour (R) Classification 15Additional Descriptors 20Optional Descriptors 24Unknown Primary 25Staging of Tumours for Which No TNM Classification is Provided 25Histopathological Grading 26References 28Chapter 2 Explanatory Notes - Specific Anatomical SitesHead and Neck Tumours 34Digestive System Tumours 54Lung, Pleural and Thymic Tumours 85Bone Tumours 104Soft Tissue Tumours 106Gastrointestinal Stromal Tumour (GIST) 108Skin Tumours 110Breast Tumours 118Gynaecological Tumours 122Urological Tumours 131Ophthalmic Tumours 142Hodgkin and Non-Hodgkin Lymphomas 149References 150Chapter 3 Site-Specific Requirements for pT and pNIntroduction 157Head and Neck Tumours 160Digestive System Tumours 166Lung and Pleural Tumours 173Tumours of Bone and Soft Tissues 176Skin Tumours 179Breast Tumours 183Gynaecological Tumours 185Urological Tumours 188Adrenal Cortex Tumours 192Ophthalmic Tumours 193Hodgkin and Non-Hodgkin Lymphomas 195References 196Chapter 4 New TNM Classifications Recommended for Testing and Other ClassificationsIntroduction 198General 198Specific 198Non Upper Aerodigestive Tract Mucosal Melanoma 199Primary Liver Carcinoma of Infants and Children/Hepatoblastoma 200Primary Cutaneous Lymphomas 202Cutaneous T-Cell Lymphomas 202Primary Cutaneous Lymphomas 203Histopathologic Staging of Lymph Nodes in Mycosis Fungoides and Sézary Syndrome 204Primary Cutaneous B-Cell/T-Cell Lymphoma (Non-MF/SS Lymphoma) 206Multiple Myeloma 207Leukaemia 208References 208Chapter 5 Optional Proposals for Testing New Subcategories of TNMAll Tumour Sites 210Head and Neck Tumours 210Digestive System Tumours 211Lung Tumours 213Breast Tumours (ICD-0-3 C50) 214Gynaecological Tumours 215Urological Tumours 215References 216Chapter 6 Frequently Asked QuestionsGeneral Questions 218Site-Specific Questions 229References 289Index 291Plate section facing p. 48