UICC Manual of Clinical Oncology

The Manual of Clinical Oncology, Ninth Edition, published with the International Union Against Cancer (UICC), provides a concise, accessible and feasible reference covering state of art multidisciplinary clinical oncology in order to meet the needs of clinicians caring for cancer patients throughout the world. Edited by world-renowned practising oncologists and written by key opinion leaders, this book contains authoritative and up-to-date information on cancer detection, diagnosis and treatment alongside topics such as survivorship, special populations and palliative care. Remodelled and revised for the ninth edition to provide practical information to oncology workers, the UICC Manual of Clinical Oncology is structured in two parts. Part 1 covers general principles of cancer diagnosis and management with additional attention to special settings in oncology, including supportive care and survivorship, and Part 2 covers site-specific multidisciplinary cancer management. The edition includes up-to-date summaries of all treatment modalities (medical, surgical and radiation) for all tumour sites. It also contains the latest TNM classifications outlined in the TNM Classification of Malignant Tumours. The ninth edition includes:Practical presentation with bullet points, tables, and flow charts intended to facilitate quick reference for day-to-day clinical practice in busy oncology environments, Representation of multidisciplinary care for site specific management, Evidence-based approaches to management, including specific treatment recommendations and investigations guided by clinical practice guidelines, State of art evidence-based recommendations that take into consideration the lack of availability of certain medications or resources, as well as practice variations, in different and remote regions of the world, and Contemporary topics on cancer treatment, such as cancer informatics, evidence levels, principles of prognostication, survivorship and cancer in pregnancy. Oncologists, oncologists-in-training, nurses working with cancer patients and other health professionals responsible for treating and caring for those with cancers will find the UICC Manual of Clinical Oncology an indispensable and comprehensive resource.

The Manual of Clinical Oncology, Ninth Edition, published with the International Union Against Cancer (UICC), provides a concise, accessible and feasible reference covering state of art multidisciplinary clinical oncology in order to meet the needs of clinicians caring for cancer patients throughout the world.Edited by world-renowned practising oncologists and written by key opinion leaders, this book contains authoritative and up-to-date information on cancer detection, diagnosis and treatment alongside topics such as survivorship, special populations and palliative care.Remodelled and revised for the ninth edition to provide practical information to oncology workers, the UICC Manual of Clinical Oncology is structured in two parts. Part 1 covers general principles of cancer diagnosis and management with additional attention to special settings in oncology, including supportive care and survivorship, and Part 2 covers site-specific multidisciplinary cancer management. The edition includes up-to-date summaries of all treatment modalities (medical, surgical and radiation) for all tumour sites. It also contains the latest TNM classifications outlined in the TNM Classification of Malignant Tumours.The ninth edition includes:Practical presentation with bullet points, tables, and flow charts intended to facilitate quick reference for day-to-day clinical practice in busy oncology environmentsRepresentation of multidisciplinary care for site specific managementEvidence-based approaches to management, including specific treatment recommendations and investigations guided by clinical practice guidelinesState of art evidence-based recommendations that take into consideration the lack of availability of certain medications or resources, as well as practice variations, in different and remote regions of the world, andContemporary topics on cancer treatment, such as cancer informatics, evidence levels, principles of prognostication, survivorship and cancer in pregnancy.Oncologists, oncologists-in-training, nurses working with cancer patients and other health professionals responsible for treating and caring for those with cancers will find the UICC Manual of Clinical Oncology an indispensable and comprehensive resource.

Foreword xPreface xiAbout the Editors xiiiContributors xviPART 1 General principles of cancer diagnosis and management 1Principles of knowledge generation and translation1 - Cancer epidemiology 32 - Levels of evidence, guidelines and standards 123 - Prognosis and classification of cancer 234 - Principles of cancer staging 345 - Assessment of treatment outcome 406 - Cancer informatics 53Principles of cancer diagnosis7 - Imaging 638 - Pathology 83Principles of treatment9 - Principles of surgery 9810 - Principles of radiotherapy 10811 - Principles of systemic therapy 124Special settings, supportive care and survivorship12 - Treatment in pregnancy 13413 - Treatment in the elderly 13914 - Oncology emergencies 14515 - Supportive care during curative treatment 15516 - Pain management in cancer 16817 - Palliative care 17418 - Survivorship 18419 - Rehabilitation 194PART 2 Site-specific multidisciplinary cancer management 203Thoracic malignancies20 - Lung 205Breast21 - Breast 221Gastrointestinal malignancies22 - Liver 24123 - Biliary tract and pancreas 26323.1 - Biliary tract 26323.2 - Pancreas 27024 - Oesophagus 28025 - Stomach 29726 - Colon, rectum and anus 30826.1 - Colon and rectum 30826.2 - Anus 327Genitourinary malignancies27 - Prostate 33328 - Bladder and other urothelium 34329 - Kidney 35430 - Testicular germ cell tumours 36831 - Penis 384Haematological malignancies32 - Lymphoma 39233 - Myeloma 41534 - Leukaemia 427Gynaecological cancers35 - Cervix 44936 - Uterus 46737 - Ovary and fallopian tube 479Head and neck cancer39 - General principles of head and neck cancer management 50340 - Nasopharynx 51241 - Oral cavity 52442 - Larynx and hypopharynx 54243 - Oropharynx 55944 - Major salivary glands 57145 - Nasal cavity and paranasal sinus 58646 - Head and neck unknown primary 597Endocrine tumors47 - Pituitary 60948 - Thyroid 62649 - Adrenal tumours 64150 - Neuroendocrine tumours 656Dermatological cancer51 - Skin: Basal cell carcinoma, squamous cell carcinoma and Merkel cell carcinoma 67452 - Melanoma 689Central nervous system and ocular cancers53 - Central nervous system 70654 - Eye: Choroidal melanoma, retinoblastoma, ocular adnexal lymphSarcoma55 - Bone (osteosarcoma) 74556 - Soft tissue 754Childhood malignancies57 - Paediatric tumors 768Specific cancer situations58 - Cancer of unknown primary (no 59 - HIV and transplant-related neoplasms 79759.1 - HIV-related neoplasms 79759.2 - Post-transplantation lymphoproliferative disease 80959.3 - Cancer following solid organ transplantation 812Index 815