Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods

Debasis Bagchi, Ph.D., MACN, CNS, MAIChE
University of Houston College of Pharmacy, Houston, TX, USA
 
Anand Swaroop, Ph.D.
Cepham Inc., Piscataway, NJ, USA
 
Manashi Bagchi, Ph.D., FACN
Cepham Inc., Piscataway, NJ, USA

Functional foods and nutraceuticals have received considerable interest in the past decade largely due to increasing consumer awareness of the health benefits associated with food. Diet in human health is no longer a matter of simple nutrition: consumers are more proactive and increasingly interested in the health benefits of functional foods and their role in the prevention of illness and chronic conditions. This, combined with an aging population that focuses not only on longevity but also quality of life, has created a market for functional foods and nutraceuticals.
 
A fully updated and revised second edition, Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods reflects the recent upsurge in "omics" technologies and features 48 chapters that cover topics including genomics, proteomics, metabolomics, epigenetics, peptidomics, nutrigenomics and human health, transcriptomics, nutriethics and nanotechnology. This cutting-edge volume, written by a panel of experts from around the globe reviews the latest developments in the field with an emphasis on the application of these novel technologies to functional foods and nutraceuticals.

Functional foods and nutraceuticals have received considerable interest in the past decade largely due to increasing consumer awareness of the health benefits associated with food.

Contributors xxiv
 
Preface xxxi
 
Part I Introduction 1
 
1 Novel Omics Technologies in Food Nutrition 3
Xuewu Zhang, Lijun You, Wei Wang, and Kaijun Xiao
 
2 Seafood Authentication using Foodomics: Proteomics, Metabolomics, and Genomics 14
Karola Böhme, Jorge Barros-Velázquez, Pilar Calo-Mata, José M. Gallardo, and Ignacio Ortea
 
3 A Foodomics Approach Reveals Hypocholesterolemic Activity of Red Microalgae 31
Irit Dvir, Aliza H. Stark, and Shoshana (Malis) Arad
 
Part II Genomics 41
 
4 Gene?]Diet Interaction and Weight Management 43
Lu Qi
 
5 NutrimiRomics: The Promise of a New Discipline in Nutrigenomics 53
Amitava Das and Chandan K. Sen
 
6 Genomics as a Tool to Characterize Anti?]inflammatory Nutraceuticals 61
Amitava Das, Scott Chaffee, and Sashwati Roy
 
7 Nutrigenomics, Inflammaging, and Osteoarthritis: A Review 71
Ali Mobasheri, Richard Barrett-Jolley, Caroline A. Staunton, Chris Ford, and Yves Henrotin
 
8 Genetic Basis of Anti-Inflammatory Properties of Boswellia Extracts 85
Golakoti Trimurtulu, Chandan K. Sen, Alluri V. Krishnaraju, Kiran Bhupathiraju, and Krishanu Sengupta
 
9 Cancer Chemopreventive Phytochemicals Targeting NF-kappaB and Nrf2 Signaling Pathways 102
Hye-Kyung Na and Young-Joon Surh
 
10 The Beneficial Health Effects of Fucoxanthin 122
Kazuo Miyashita and Masashi Hosokawa
 
11 Nutrition, Genomics, and Human Health: A Complex Mechanism for Wellness 135
Okezie I. Aruoma
 
12 Application of Genomics and Bioinformatics Analysis in Exploratory Study of Functional Foods 140
Kohsuke Hayamizu and Aiko Manji
 
13 Omics Analysis and Databases for Plant Science 150
Masaaki Kobayashi, Hajime Ohyanagi, and Kentaro Yano
 
14 Synergistic Plant Genomics and Molecular Breeding Approaches for Ensuring Food Security 160
Shouvik Das and Swarup K. Parida
 
15 Combinatorial Approaches Utilizing Nutraceuticals in Cancer Chemoprevention and Therapy: A Complementary Shift with Promising Acuity 185
Madhulika Singh and Yogeshwer Shukla
 
16 Nutrigenomic Approaches to Understanding the Transcriptional and Metabolic Responses of Phytochemicals to Diet-Induced Obesity and its Complications 218
Myung-Sook Choi and Eun-Young Kwon
 
17 Going Beyond the Current Native Nutritional Food Through the Integration of the Omic Data in the Post?]Genomic Era: A Study in (Resistant) Starch Systems Biology 230
Treenut Saithong and Saowalak Kalapanulak
 
Part III Proteomics 243
 
18 Proteomics and Nutrition Research: An Overview 245
Arun K. Tewari, Sudhasri Mohanty, and Sashwati Roy
 
19 Proteomics Analysis for the Functionality of Toona sinensis 253
Sue-Joan Chang and Chun-Yung Huang
 
20 Proteomic Approaches to Identify Novel Therapeutics and Nutraceuticals from Filamentous Fungi: Prospects and Challenges 265
Samudra Prosad Banik, Suman Khowala, Chiranjib Pal, and Soumya Mukherjee
 
21 Proteomics and Metaproteomics for Studying Probiotic Activity 296
Rosa Anna Siciliano and Maria Fiorella Mazzeo
 
22 Proteomics Approach to Assess the Potency of Dietary Grape Seed Proanthocyanidins and Dimeric Procyanidin B2 304
Hai-qing Gao, Bao-ying Li, Mei Cheng, Xiao-li Li, Fei Yu, and Zhen Zhang
 
23 Genomic and Proteomic Approaches to Lung Transplantation: Identifying Relevant Biomarkers to Improve Surgical Outcome 321
John Noel, Ronald Carnemola, and Shampa Chatterjee
 
24 Proteomics in Understanding the Molecular Basis of Phytochemicals for Health 328
Jung Yeon Kwon, Sanguine Byun, and Ki Won Lee
 
25 Genomics/Proteomics of NEXT-II, a Novel Water?]Soluble, Undenatured Type II Collagen in Joint Health Care 338
Orie Yoshinari, Hiroyoshi Moriyama, Manashi Bagchi, and