Neuroendocrinology of Stress

Exposure to chronic stress has cumulative adverse effects on physical and mental health, considered to be the consequence of chronic exposure to high levels of stress hormones. Consequently, there is extensive research in progress to investigate and better understand how the brain organises neuroendocrine stress responses and how interventions may be able to moderate these responses to improve mental and physical health. Neuroendocrinology of Stress highlights current knowledge of the organisation and physiology of these stress response systems, how the impact of dysregulation of these systems is being investigated, and considers the ways in which contributions to both psychiatric and physical diseases resulting from chronic stress effects can be critically addressed in basic research Written by a team of internationally renowned researchers, each chapter presents a succinct summary of the very latest developments in the field Both print and enhanced e-book versions are available Illustrated in full colour throughout This is the second volume in a new Series "e;Masterclass in Neuroendocrinology"e;, a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Exposure to chronic stress has cumulative adverse effects on physical and mental health, considered to be the consequence of chronic exposure to high levels of stress hormones. Consequently, there is extensive research in progress to investigate and better understand how the brain organises neuroendocrine stress responses and how interventions may be able to moderate these responses to improve mental and physical health.Neuroendocrinology of Stress highlights current knowledge of the organisation and physiology of these stress response systems, how the impact of dysregulation of these systems is being investigated, and considers the ways in which contributions to both psychiatric and physical diseases resulting from chronic stress effects can be critically addressed in basic research* Written by a team of internationally renowned researchers, each chapter presents a succinct summary of the very latest developments in the field* Both print and enhanced e-book versions are available* Illustrated in full colour throughoutThis is the second volume in a new Series "Masterclass in Neuroendocrinology", a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

List of Contributors, viiSeries Preface, ixPreface, xiAbout the Companion Website, xv1 Methods and Approaches to Understand Stress Processing Circuitry, 1James P. Herman and Brent Myers2 Brain Monoaminergic Systems in Stress Neuroendocrinology, 19Matthew W. Hale and Christopher A. Lowry3 The Synaptic Physiology of the Central Nervous System Response to Stress, 43Jeffrey G. Tasker and Marian Joëls4 Illuminating the (Electro)physiology of Anterior Pituitary Corticotrophs, 71Lie Chen, Peter Duncan, Duncan Macgregor, Zhi Liang and Michael J. Shipston5 Stress and Sympathoadrenomedullary Mechanisms, 95Regina Nostramo and Esther L. Sabban6 Neuroendocrine Mechanisms of Stress Regulation in Humans, 121Jens C. Pruessner and Nida Ali7 Studying Chronic Stress in Animals: Purposes, Models and Consequences, 143Antonio Armario8 Modelling Stress-Related Mood Disorders in Animals, 169Mathias V. Schmidt, Klaus V. Wagner, Xiao-Dong Wang and Georgia Balsevich9 Glucocorticoid Involvement in Drug Abuse and Addiction, 195John R. Mantsch and Paul J. Gasser10 The Hypothalamic-Pituitary-Adrenal Axis: Circadian Dysregulation and Obesity, 219Andries Kalsbeek, Yan Su, Eric Fliers and Susanne la Fleur11 Using Rodent Models to Explore the Role of 11beta-Hydroxysteroid Dehydrogenase 2 (11beta-HSD2) in Prenatal Programming by Glucocorticoids, 245Caitlin Wyrwoll, Anjanette Harris and Megan Holmes12 Early-Life Stress: Rodent Models, Lessons and Challenges, 265Pamela M. Maras and Tallie Z. Baram13 Mothering Influences on Offspring Stress Response Mechanisms, 287Claire-Dominique Walker and Barbara Woodside14 Translational Research in Stress Neuroendocrinology: 11beta-Hydroxysteroid Dehydrogenase 1 (11beta-HSD1), A Case Study, 327Rebecca M. Reynolds and Scott P. WebsterGlossary, 351Index, 369