Translational Vascular Medicine

Translational medicine underpins vascular medicine. It is fundamental to understanding how we treat patients with vascular disease and more importantly, how to prevent it. It is the rationale for drug design and production. Vascular medicine and translational medicine will take over and become the main reason for referring patients to hospital. Therefore, hospital-based clinicians working with basic scientists need to know about translational medicine, which educates and informs them about vascular medicine and how management should be based.

Newly qualified and trained physicians are working in multidisciplinary groups of cardiologists, vascular surgeons, cardiac surgeons, lipidologists, diabetologists. Clinicians in the US, Australasia, the Far East and western Europe are interested in the molecular basis and treatments of vascular medicine and this encompasses translational medicine.

This book is a primer for translational vascular medicine and discusses the evolving and exciting areas of basic science applied to vascular medicine. The book is based on the third vascular biology conference held at The Royal College of Physicians in 2008. It provides a large amount of new basic and clinical information and the contributors are world leaders.

Translational medicine underpins vascular medicine. It is fundamental to understanding how we treat patients with vascular disease and more importantly, how to prevent it. It is the rationale for drug design and production. Vascular medicine and translational medicine will take over and become the main reason for referring patients to hospital. Therefore, hospital-based clinicians working with basic scientists need to know about translational medicine, which educates and informs them about vascular medicine and how management should be based.

This book is a primer for translational vascular medicine and discusses the evolving and exciting areas of basic science applied to vascular medicine. The book is based on the third vascular biology conference held at The Royal College of Physicians in 2008. It provides a large amount of new basic and clinical information and the contributors are world leaders.

Preface
Foreword
Section 1: Vascular Biology
1. The Biology of Endothelin
2. Endogenous inhibitors of NO synthesis
3. Pericytes: Adaptable vascular progenitors
4. Free radicals and oxidant stress

Section 2: Complications and Treatments in Human Vascular Disease
5. Genomics and cardiovascular disease 
6. Surgical trauma and graft performance in patients undergoing coronary artery bypass surgery    

Section 3: Clinical and Basic Aspects of Vascular Medicine
7. Pulmonary Arterial Hypertension
8. Inflammation in pulmonary arterial hypertension
9. Cell therapy for cardiovascular disease
10. Clinical applications of CV Imaging
11. Cardiovascular disease in women

Session 4: Surgical intervention for Vascular Complications
12. Non-pharmacological treatment of peripheral vascular disease
13. Surgical approaches to aneurysm repair
14. Delivering improving treatment for cardiovascular disease