Bioinformatics for Vaccinology

this book was written from start to finish by one extremely dedicated and erudite individual. The author has done an excellent job of covering the many topics that fall under the umbrella of computational biology for vaccine design, demonstrating an admirable command of subject matter in fields as disparate as object-oriented databases and regulation of T cell response. Simply put, it has just the right breadth and depth, and it reads well. In fact, readability is one of its virtues making the book enticing and useful, all at once Human Vaccines, 2010 "e;... This book has several strong points. Although there are many textbooks that deal with vaccinology, few attempts have been made to bring together descriptions of vaccines in history, basic bioinformatics, various computational solutions and challenges in vaccinology, detailed experimental methodologies, and cutting-edge technologies... This book may well serve as a first line of reference for all biologists and computer scientists..."e; Virology Journal, 2009 Vaccines have probably saved more lives and reduced suffering in a greater number of people than any other medical intervention in human history, succeeding in eradicating smallpox and significantly reducing the mortality and incidence of other diseases. However, with the emergence of diseases such as SARS and the threat of biological warfare, vaccination has once again become a topic of major interest in public health. Vaccinology now has at its disposal an array of post-genomic approaches of great power. None has a more persuasive potential impact than the application of computational informatics to vaccine discovery; the recent expansion in genome data and the parallel increase in cheap computing power have placed the bioinformatics exploration of pathogen genomes centre stage for vaccine researchers. This is the first book to address the area of bioinformatics as applied to rational vaccine design, discussing the ways in which bioinformatics can contribute to improved vaccine development by introducing the subject of harnessing the mathematical and computing power inherent in bioinformatics to the study of vaccinology putting it into a historical and societal context, and exploring the scope of its methods and applications. Bioinformatics for Vaccinology is a one-stop introduction to computational vaccinology. It will be of particular interest to bioinformaticians with an interest in immunology, as well as to immunologists, and other biologists who need to understand how advances in theoretical and computational immunobiology can transform their working practices.

"... this book was written from start to finish by oneextremely dedicated and erudite individual. The author has done anexcellent job of covering the many topics that fall under theumbrella of computational biology for vaccine design, demonstratingan admirable command of subject matter in fields as disparate asobject-oriented databases and regulation of T cell response. Simplyput, it has just the right breadth and depth, and it reads well. Infact, readability is one of its virtues--making the bookenticing and useful, all at once..." Human Vaccines2010"... This book has several strong points. Although there aremany textbooks that deal with vaccinology, few attempts have beenmade to bring together descriptions of vaccines in history, basicbioinformatics, various computational solutions and challenges invaccinology, detailed experimental methodologies, and cutting-edgetechnologies... This book may well serve as a first line ofreference for all biologists and computer scientists..."Virology Journal, 2009Vaccines have probably saved more lives and reduced suffering in agreater number of people than any other medical intervention inhuman history, succeeding in eradicating smallpox and significantlyreducing the mortality and incidence of other diseases. Howeverwith the emergence of diseases such as SARS and the threat ofbiological warfare, vaccination has once again become a topic ofmajor interest in public health.Vaccinology now has at its disposal an array of post-genomicapproaches of great power. None has a more persuasive potentialimpact than the application of computational informatics to vaccinediscovery; the recent expansion in genome data and the parallelincrease in cheap computing power have placed the bioinformaticsexploration of pathogen genomes centre stage for vaccineresearchers.This is the first book to address the area of bioinformatics asapplied to rational vaccine design, discussing the ways in whichbioinformatics can contribute to improved vaccine developmentby* introducing the subject of harnessing the mathematical andcomputing power inherent in bioinformatics to the study ofvaccinology* putting it into a historical and societal contextand* exploring the scope of its methods and applications.Bioinformatics for Vaccinology is a one-stopintroduction to computational vaccinology. It will be of particularinterest to bioinformaticians with an interest in immunology, aswell as to immunologists, and other biologists who need tounderstand how advances in theoretical and computationalimmunobiology can transform their working practices.