The Melanocytic Proliferations

Cynthia M. Magro, MD, is Professor of Pathology and Director of Dermatopathology at Weill Medical College of Cornell University in New York City. She has published extensively in the areas of inflammatory skin disease, including collagen vascular disease, vasculitis, cutaneous manifestations of systemic disease, and unique drug hypersensitivity reactions. A significant focus of her work has been lymphocytic infiltrates, including unique forms of drug reactions such as the interstitial granulomatous drug reaction and drug-associated reversible T cell dyscrasia; prelymphomatous cutaneous lymphoid dyscrasias including atypical lymphocytic lobular panniculitis pityriasis lichenoides chronica and pigmented purpuric dermatosis; and malignant T and B cell lymphomas. She has extended her work in immune mechanisms of skin disease and applied it to areas of lung transplantation and pulmonary fibrosis.

A thorough updating of the best-selling, vital reference and textbook on melanocytic proliferations
 
PRAISE FOR THE FIRST EDITION:
 
"Well-written and entertaining"
--Modern Pathology
 
"An extremely helpful guide for the practicing dermatopathologist or general pathologist"
--Archives of Pathology and Laboratory Medicine
 
"An incredibly relevant clinical-histopathologic text"
--Doody's
 
Melanocytic proliferations comprise a large number of pigmented lesions of the skin and muscosa. Of these, melanoma is of particular interest to clinicians and their patients. The rising number of incidences of melanoma has led to increased interest in the disease from diagnostic, management, and basic science perspectives.
 
The Melanocytic Proliferations: A Comprehensive Textbook of Pigmented Lesions is the most complete single-source treatment of the subject available--thoroughly updated to reflect the very latest studies and clinical experience in diagnosing and treating melanocytic proliferation. This new edition of the bestseller presents an experience- and evidence-based review of pigmented lesions that encompasses the biology, diagnosis, and treatment of melanocytic proliferations and disorders, including melanoma. It comes with over 300 new color images--bringing the total to over 600--and contains two completely new chapters: Dermatoscopic Diagnosis of Melanoma; and Reflectance Confocal Microscopy.
 
Chapter coverage includes:
* An approach to the clinical diagnosis of melanoma, its precursors, and its clinical mimics
* Freckles and lentigines
* Benign acquired nevi
* Dermal dendritic melanocytic proliferations/dermal melanocytoses
* Spitz nevus
* Combined nevus, deep penetrating nevus, plexiform spindle cell nevus, and borderline tumors of the deep penetrating nevus variant
* Recurrent melanocytic nevus
* Congenital nevi
* Dysplastic melanocytic nevi, de novo intradermal epithelioid and lentiginous melanocytic dysplasias, and nevi at specific anatomic sites
* Melanoma
* Conjunctival melanocytic proliferations
* Use of adjunctive immunoperoxidase, molecular, and ultrastructural studies in the diagnosis of melanocytic proliferations
* Biology of melanoma
* Borderline melanocytic proliferation
* Dermatoscopic diagnosis of melanoma
* Reflectance confocal microscopy
* Therapy of melanoma
 
The Melanocytic Proliferations: A Comprehensive Textbook of Pigmented Lesions is an incredibly important text for all clinical pathologists, dermatopathologists, surgical pathologists, dermatologists, cosmetic physicians, and surgeons.

Dedication, vii
 
Preface, viii
 
Disclosure, ix
 
About the Companion Website, x
 
1 An Approach to the Clinical Diagnosis of Melanoma, Its Precursors, and Its Clinical Mimics, 1
 
2 Freckles and Lentigines, 44
 
3 Benign Acquired Nevi, 65
 
4 Dermal Dendritic Melanocytic Proliferations/Dermal Melanocytoses, 85
 
5 Spitz Nevus, 107
 
6 Combined Nevus, Deep Penetrating Nevus, Plexiform Spindle Cell Nevus, and Borderline Tumors of the Deep Penetrating Nevus Variant, 164
 
7 Recurrent Melanocytic Nevus, 175
 
8 Congenital Nevi, 187
 
9 Dysplastic Melanocytic Nevi, De Novo Intradermal Epithelioid and Lentiginous Melanocytic Dysplasias, and Nevi at Specific Anatomic Sites, 201
 
10 Melanoma, 254
 
11 Conjunctival Melanocytic Proliferations, 365
 
12 Use of Adjunctive Immunoperoxidase, Molecular, and Ultrastructural Studies in the Diagnosis of Melanocytic Proliferations, 380
 
13 Biology of Melanoma, 412
 
14 Borderline Melanocytic Proliferation, 443
 
15 Dermatoscopic Diagnosis of Melanoma, 467
 
16 Reflectance Confocal Microscopy, 474
 
17 Therapy of Melanoma, 488
 
Index, 510