The Engines of Hippocrates

A unique, integrative look at information-based medicine The convergence of medical science, biology, pharmacology, biomedical engineering, healthcare, and information technology is revolutionizing medical and scientific practice, and has broader social implications still being understood. The Engines of Hippocrates provides a unique, integrative, and holistic look at the new paradigm of information-based medicine, covering a broad range of topics for a wide readership. The authors take a comprehensive approach, examining the prehistory, history, and future of medicine and medical technology and its relation to information; how history led to such present-day discoveries as the structure of DNA, the human genome, and the discipline of bioinformatics; and what the future results of these discoveries may hold. Their far-ranging views are their own and not necessarily those of the IBM Corporation or other employers. The Engines of Hippocrates helps readers understand: Forces shaping the pharmaceutical and biomedical industries today, including personalized medicine, genomics, data mining, and bionanotechnology The relationship between pharmaceutical science today and other disciplines such as philosophy of health, history, economics, mathematics, and computer science The integrated role alternative and non-Western medicines could play in a new, information-based medicine Practical, ethical, organizational, technological, and social problems of information-based medicine, along with a novel data-centric computing model and a self-adaptive software engineering model, and corresponding information technology architectures, including perspectives on sharing remote data efficiently and securely for the common good An unmatched, cross-disciplinary perspective on the big picture of today and tomorrow's medicine, The Engines of Hippocrates provides a reference to interested readers both inside and outside the pharmaceutical and medical communities, as well as a peerless classroom supplement to students in a wide variety of disciplines.

A unique, integrative look at information-based medicineThe convergence of medical science, biology, pharmacologybiomedical engineering, healthcare, and information technology isrevolutionizing medical and scientific practice, and has broadersocial implications still being understood. The Engines ofHippocrates provides a unique, integrative, and holistic lookat the new paradigm of information-based medicine, covering a broadrange of topics for a wide readership.The authors take a comprehensive approach, examining theprehistory, history, and future of medicine and medical technologyand its relation to information; how history led to suchpresent-day discoveries as the structure of DNA, the human genomeand the discipline of bioinformatics; and what the future resultsof these discoveries may hold. Their far-ranging views are theirown and not necessarily those of the IBM Corporation or otheremployers.The Engines of Hippocrates helps readers understand:* Forces shaping the pharmaceutical and biomedical industriestoday, including personalized medicine, genomics, data mining, andbionanotechnology* The relationship between pharmaceutical science today and otherdisciplines such as philosophy of health, history, economicsmathematics, and computer science* The integrated role alternative and non-Western medicines couldplay in a new, information-based medicine* Practical, ethical, organizational, technological, and socialproblems of information-based medicine, along with a noveldata-centric computing model and a self-adaptive softwareengineering model, and corresponding information technologyarchitectures, including perspectives on sharing remote dataefficiently and securely for the common goodAn unmatched, cross-disciplinary perspective on the big pictureof today and tomorrow's medicine, The Engines of Hippocratesprovides a reference to interested readers both inside and outsidethe pharmaceutical and medical communities, as well as a peerlessclassroom supplement to students in a wide variety ofdisciplines.

Preface.About the Authors.1 A Short Preview of Mankind, Medicine, Molecules, andMachines.2 From Prehistory to Hippocrates.3 The Road to the New Medicine.4 The Imminent Challenge: Medicine as an Industry.5 The Next Decade: Personalized Medicine and the Digital PatientRecord.6 Enforcing your Rights: Medical Ethics, Consent, Privacy, andIT.7 Holistic Medicine and IT.8 Architecting It All.9 Guardian Angels: Knowing Our Molecules, Drug and VaccineDesign, Medical Decision Support, Medical Vigilance andDefense.10 What Next? At One with the Engines of Hippocrates.Glossary.Clinical Trial Terms.Notes, Bibliography, and Further Reading Guide.Index.