Bücher online kaufen
Smith and Williams’ Introduction to the Principles of Drug Design and Action
-0 %
Besorgungstitel - wird vorgemerkt | Lieferzeit: Besorgungstitel - Lieferbar innerhalb von 10 Werktagen I
Artikel-Nr:
9780415288774
Veröffentl:
2005
Erscheinungsdatum:
10.10.2005
Seiten:
682
Autor:
H. John Smith
Gewicht:
1601 g
Format:
261x181x43 mm
Sprache:
Deutsch
Beschreibung:
H. John Smith, Hywel Williams
As knowledge of biological systems and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. Smith and Williams' Introduction to the Principles of Drug Design and Action, Fourth Edition provides the basic principles of rational drug design, including both novel and established approaches. This new edition adopts a from-bench-to-marketplace approach, using real examples where possible. It offers a comprehensive update of the previous edition, particularly with respect to new advances in molecular techniques, biotechnological applications, and computer-aided design.
Processes of Drug Handling by the Body. The Design of Drug Delivery Systems. Fundamental Pharmacokinetics. Intermolecular Forces and Molecular Modeling. Drug Chirality and its Pharmacological Consequences. Quantitative Structure-Activity Relationships (QSAR) in Drug Design. Prodrugs. From Program Sanction to Clinical Trials: A Partial View of the Quest for Arimidex, A Potent, Selective Inhibitor of Aromatase. Design of Enzyme Inhibitors as Drugs. Peptide Drug Design. Combinatorial Chemistry: A Tool for Drug Discovery. Recombinant DNA Technology: Monoclonal Antibodies. The Human Genome and its Impact on Drug Discovery and Therapy. The Chemotherapy of Cancer. Neurotransmitters, Agonists, and Antagonists. Design of Antibacterial, Antifungal, and Antiviral Agents. Pharmaceutical Applications of Bioinorganic Chemistry. Index.